Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator
As the decay daughter of 99Mo, 99mTc is the most widely used radioisotope in the field of nuclear medicine. Recently, the major 99Mo production reactors in the world are facing problems such as unplanned maintenance, shutdown and decommission, resulting in the unstable supply of 99Mo. Therefore, man...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Board of Journal of Isotopes
2022-04-01
|
| Series: | Journal of Isotopes |
| Subjects: | |
| Online Access: | http://www.tws.org.cn/CN/10.7538/tws.2022.35.02.0114 |
| _version_ | 1811308273241948160 |
|---|---|
| author | WANG Yi;GUO Zifang;WANG Lan;LI Jiaolong;JIAO Limin;GAO Xuan;WENG Hanqin;LIN Mingzhang |
| author_facet | WANG Yi;GUO Zifang;WANG Lan;LI Jiaolong;JIAO Limin;GAO Xuan;WENG Hanqin;LIN Mingzhang |
| author_sort | WANG Yi;GUO Zifang;WANG Lan;LI Jiaolong;JIAO Limin;GAO Xuan;WENG Hanqin;LIN Mingzhang |
| collection | DOAJ |
| description | As the decay daughter of 99Mo, 99mTc is the most widely used radioisotope in the field of nuclear medicine. Recently, the major 99Mo production reactors in the world are facing problems such as unplanned maintenance, shutdown and decommission, resulting in the unstable supply of 99Mo. Therefore, many developed countries have been actively exploiting alternative technologies for 99Mo production. In this paper, various 99Mo-production technologies by particle accelerator instead of reactor were introduced, and the research progress of producing 99Mo based on electron accelerator was summarized at home and abroad. The accelerator performance index and the key technologies in the production process were discussed in detail, such as the design of irradiation device and target, separation of 99mTc, recovery of 100Mo and waste management. In addition, some suggestions were put forward for the basic and applied research of relevant technologies in China and the commercialization of 99Mo production by electron accelerator. |
| first_indexed | 2024-04-13T09:19:10Z |
| format | Article |
| id | doaj.art-a126fdf6d4994728821bf69b906e0044 |
| institution | Directory Open Access Journal |
| issn | 1000-7512 |
| language | zho |
| last_indexed | 2024-04-13T09:19:10Z |
| publishDate | 2022-04-01 |
| publisher | Editorial Board of Journal of Isotopes |
| record_format | Article |
| series | Journal of Isotopes |
| spelling | doaj.art-a126fdf6d4994728821bf69b906e00442022-12-22T02:52:39ZzhoEditorial Board of Journal of IsotopesJournal of Isotopes1000-75122022-04-01352114127Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron AcceleratorWANG Yi;GUO Zifang;WANG Lan;LI Jiaolong;JIAO Limin;GAO Xuan;WENG Hanqin;LIN Mingzhang0School of Nuclear Science and Technology, University of Science and Technology of China；National Synchrotron Radiation Laboratory, University of Science and Technology of China；National Synchrotron Radiation Laboratory, University of Science and Technology of ChinaAs the decay daughter of 99Mo, 99mTc is the most widely used radioisotope in the field of nuclear medicine. Recently, the major 99Mo production reactors in the world are facing problems such as unplanned maintenance, shutdown and decommission, resulting in the unstable supply of 99Mo. Therefore, many developed countries have been actively exploiting alternative technologies for 99Mo production. In this paper, various 99Mo-production technologies by particle accelerator instead of reactor were introduced, and the research progress of producing 99Mo based on electron accelerator was summarized at home and abroad. The accelerator performance index and the key technologies in the production process were discussed in detail, such as the design of irradiation device and target, separation of 99mTc, recovery of 100Mo and waste management. In addition, some suggestions were put forward for the basic and applied research of relevant technologies in China and the commercialization of 99Mo production by electron accelerator.http://www.tws.org.cn/CN/10.7538/tws.2022.35.02.0114electron acceleratormedical isotope99mo99mtcphotonuclear reaction |
| spellingShingle | WANG Yi;GUO Zifang;WANG Lan;LI Jiaolong;JIAO Limin;GAO Xuan;WENG Hanqin;LIN Mingzhang Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator Journal of Isotopes electron accelerator medical isotope 99mo 99mtc photonuclear reaction |
| title | Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator |
| title_full | Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator |
| title_fullStr | Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator |
| title_full_unstemmed | Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator |
| title_short | Development Status and Prospect for the Medical Isotope Molybdenum-99 Produced by Electron Accelerator |
| title_sort | development status and prospect for the medical isotope molybdenum 99 produced by electron accelerator |
| topic | electron accelerator medical isotope 99mo 99mtc photonuclear reaction |
| url | http://www.tws.org.cn/CN/10.7538/tws.2022.35.02.0114 |
| work_keys_str_mv | AT wangyiguozifangwanglanlijiaolongjiaolimingaoxuanwenghanqinlinmingzhang developmentstatusandprospectforthemedicalisotopemolybdenum99producedbyelectronaccelerator |