NAD<sup>+</sup> Precursors Reverse Experimental Diabetic Neuropathy in Mice

NAD<sup>+</sup> Precursors Reverse Experimental Diabetic Neuropathy in Mice

Abnormal NAD<sup>+</sup> signaling has been implicated in axonal degeneration in diabetic peripheral neuropathy (DPN). We hypothesized that supplementing NAD<sup>+</sup> precursors could alleviate DPN symptoms through increasing the NAD<sup>+</sup> levels and acti...

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Bibliographic Details
Main Authors: Krish Chandrasekaran, Neda Najimi, Avinash R. Sagi, Sushuma Yarlagadda, Mohammad Salimian, Muhammed Ikbal Arvas, Ahmad F. Hedayat, Yanni Kevas, Anand Kadakia, Tibor Kristian, James W. Russell
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
streptozotocin
high fat diet
diabetic neuropathy
NAD<sup>+</sup>
mitochondria
SIRT1
Online Access:https://www.mdpi.com/1422-0067/25/2/1102

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