Carbon dioxide inhibits UVB-induced inflammatory response by activating the proton-sensing receptor, GPR65, in human keratinocytes
Abstract Carbon dioxide (CO2) is the predominant gas molecule emitted during aerobic respiration. Although CO2 can improve blood circulation in the skin via its vasodilatory effects, its effects on skin inflammation remain unclear. The present study aimed to examine the anti-inflammatory effects of...
Main Authors: | Keimon Sayama, Katsuyuki Yuki, Keiichi Sugata, Satoko Fukagawa, Tetsuji Yamamoto, Shigaku Ikeda, Takatoshi Murase |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-79519-0 |
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