Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors

Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The deve...

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Main Authors: Franco Cosi, Silvia Soria, Gualtiero Nunzi Conti, Francesco Baldini, Ambra Giannetti, Simone Berneschi
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/12/11/14604
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author Franco Cosi
Silvia Soria
Gualtiero Nunzi Conti
Francesco Baldini
Ambra Giannetti
Simone Berneschi
author_facet Franco Cosi
Silvia Soria
Gualtiero Nunzi Conti
Francesco Baldini
Ambra Giannetti
Simone Berneschi
author_sort Franco Cosi
collection DOAJ
description Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
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spelling doaj.art-a12cbdb5ec334b30936617f0d5de42712022-12-22T04:22:58ZengMDPI AGSensors1424-82202012-10-011211146041461110.3390/s121114604Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based ImmunosensorsFranco CosiSilvia SoriaGualtiero Nunzi ContiFrancesco BaldiniAmbra GiannettiSimone BerneschiWhispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.http://www.mdpi.com/1424-8220/12/11/14604whispering gallery mode resonatorsimmunosensorsEudragit
spellingShingle Franco Cosi
Silvia Soria
Gualtiero Nunzi Conti
Francesco Baldini
Ambra Giannetti
Simone Berneschi
Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
Sensors
whispering gallery mode resonators
immunosensors
Eudragit
title Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_full Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_fullStr Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_full_unstemmed Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_short Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_sort performance of eudragit coated whispering gallery mode resonator based immunosensors
topic whispering gallery mode resonators
immunosensors
Eudragit
url http://www.mdpi.com/1424-8220/12/11/14604
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AT francescobaldini performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors
AT ambragiannetti performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors
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