Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The deve...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-10-01
|
Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/12/11/14604 |
_version_ | 1828116606702583808 |
---|---|
author | Franco Cosi Silvia Soria Gualtiero Nunzi Conti Francesco Baldini Ambra Giannetti Simone Berneschi |
author_facet | Franco Cosi Silvia Soria Gualtiero Nunzi Conti Francesco Baldini Ambra Giannetti Simone Berneschi |
author_sort | Franco Cosi |
collection | DOAJ |
description | Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution. |
first_indexed | 2024-04-11T13:00:42Z |
format | Article |
id | doaj.art-a12cbdb5ec334b30936617f0d5de4271 |
institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-04-11T13:00:42Z |
publishDate | 2012-10-01 |
publisher | MDPI AG |
record_format | Article |
series | Sensors |
spelling | doaj.art-a12cbdb5ec334b30936617f0d5de42712022-12-22T04:22:58ZengMDPI AGSensors1424-82202012-10-011211146041461110.3390/s121114604Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based ImmunosensorsFranco CosiSilvia SoriaGualtiero Nunzi ContiFrancesco BaldiniAmbra GiannettiSimone BerneschiWhispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.http://www.mdpi.com/1424-8220/12/11/14604whispering gallery mode resonatorsimmunosensorsEudragit |
spellingShingle | Franco Cosi Silvia Soria Gualtiero Nunzi Conti Francesco Baldini Ambra Giannetti Simone Berneschi Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors Sensors whispering gallery mode resonators immunosensors Eudragit |
title | Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors |
title_full | Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors |
title_fullStr | Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors |
title_full_unstemmed | Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors |
title_short | Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors |
title_sort | performance of eudragit coated whispering gallery mode resonator based immunosensors |
topic | whispering gallery mode resonators immunosensors Eudragit |
url | http://www.mdpi.com/1424-8220/12/11/14604 |
work_keys_str_mv | AT francocosi performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors AT silviasoria performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors AT gualtieronunziconti performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors AT francescobaldini performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors AT ambragiannetti performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors AT simoneberneschi performanceofeudragitcoatedwhisperinggallerymoderesonatorbasedimmunosensors |