A novel treatment strategy of HER2-targeted therapy in combination with Everolimus for HR+/HER2- advanced breast cancer patients with HER2 mutations
The incidence of HER2 somatic mutations in breast cancer is about 2–4%, mainly occurring in the HR+/HER2- subtype. Preclinical studies suggest that HER2 mutations can lead to constitutive HER2 activation, but effective treatment options for the clinical management of patients with HER2 mutations rem...
Autori principali: | , , , , , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Elsevier
2022-07-01
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Serie: | Translational Oncology |
Soggetti: | |
Accesso online: | http://www.sciencedirect.com/science/article/pii/S1936523322001036 |