A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly

Human stomatin (hSTOM) is a component of the membrane skeleton of erythrocytes that maintains the membrane's shape and stiffness through interconnecting spectrin and actin. hSTOM is a member of the protein family that possesses a single stomatin/prohibitin/flotillin/HflK (SPFH) domain at the ce...

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Bibliographic Details
Main Authors: Koki Kataoka, Shota Suzuki, Takeshi Tenno, Natsuko Goda, Emi Hibino, Atsunori Oshima, Hidekazu Hiroaki
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Structural Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X22000149