Synergistic Analysis of Circulating Tumor Cells Reveals Prognostic Signatures in Pilot Study of Treatment-Naïve Metastatic Pancreatic Cancer Patients

Synergistic Analysis of Circulating Tumor Cells Reveals Prognostic Signatures in Pilot Study of Treatment-Naïve Metastatic Pancreatic Cancer Patients

Pancreatic ductal adenocarcinoma is typically diagnosed at late stages and has one of the lowest five-year survival rates of all malignancies. In this pilot study, we identify signatures related to survival and treatment response found in circulating tumor cells (CTCs). Patients with poor survival h...

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Bibliographic Details
Main Authors: Sarah Owen, Emily Prantzalos, Valerie Gunchick, Vaibhav Sahai, Sunitha Nagrath
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
CTC
liquid biopsy
pancreatic cancer
mutant KRAS
gene expression profiling
Online Access:https://www.mdpi.com/2227-9059/10/1/146

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