<i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
<i>Streptococcus suis</i> represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decade...
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MDPI AG
2021-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/10/1314 |
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| author | Ján Matiašovic Kateřina Nedbalcová Marek Žižlavský Petr Fleischer Lucie Pokludová Dita Kellnerová Kateřina Nechvátalová Bronislav Šimek Linda Czanderlová Monika Zouharová Jan Bernardy Natálie Králová Soňa Šlosárková |
| author_facet | Ján Matiašovic Kateřina Nedbalcová Marek Žižlavský Petr Fleischer Lucie Pokludová Dita Kellnerová Kateřina Nechvátalová Bronislav Šimek Linda Czanderlová Monika Zouharová Jan Bernardy Natálie Králová Soňa Šlosárková |
| author_sort | Ján Matiašovic |
| collection | DOAJ |
| description | <i>Streptococcus suis</i> represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidity and minimize treatment. The study analysed serotypes, sequence types and antimicrobial susceptibility in 39 <i>S. suis</i> isolates obtained from organs of diseased pigs from selected 16 repopulated farms with a history of <i>S. suis</i>-associated diseases and routine antimicrobial treatment with tulathromycin and/or amoxicillin. The analysis revealed diversity of collected isolates with regular occurrence of more than three serotypes per farm. The serotypes identified were 1/2 and 7, each in six isolates, followed by serotype 2 and 3 found in five isolates each, other serotypes were less frequent. Seven isolates were not typable by multiplex PCR and we also found sequence type of unknown type in thirteen isolates. The majority of <i>S. suis</i> isolates were resistant to clindamycin (n = 31), tetracycline (n = 29) and tilmicosin and tulathromycin (n = 28). On the other hand, with the exception of two isolates that were intermediately susceptible to penicillin and ampicillin, all isolates were susceptible to all three tested subgroups of beta-lactam antibiotics. |
| first_indexed | 2024-03-10T06:17:26Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T06:17:26Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-a1308b2237304988ab471a36934fcbbf2023-11-22T19:34:10ZengMDPI AGPathogens2076-08172021-10-011010131410.3390/pathogens10101314<i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig FarmsJán Matiašovic0Kateřina Nedbalcová1Marek Žižlavský2Petr Fleischer3Lucie Pokludová4Dita Kellnerová5Kateřina Nechvátalová6Bronislav Šimek7Linda Czanderlová8Monika Zouharová9Jan Bernardy10Natálie Králová11Soňa Šlosárková12Department of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicSevaron s.r.o., 61200 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Marketing Authorisation, Institute for State Control of Veterinary Biologicals and Medicines, 62100 Brno, Czech RepublicSevaron s.r.o., 61200 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Molecular Biology, State Veterinary Institute Jihlava, 58601 Jihlava, Czech RepublicSevaron s.r.o., 61200 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute, 62100 Brno, Czech Republic<i>Streptococcus suis</i> represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidity and minimize treatment. The study analysed serotypes, sequence types and antimicrobial susceptibility in 39 <i>S. suis</i> isolates obtained from organs of diseased pigs from selected 16 repopulated farms with a history of <i>S. suis</i>-associated diseases and routine antimicrobial treatment with tulathromycin and/or amoxicillin. The analysis revealed diversity of collected isolates with regular occurrence of more than three serotypes per farm. The serotypes identified were 1/2 and 7, each in six isolates, followed by serotype 2 and 3 found in five isolates each, other serotypes were less frequent. Seven isolates were not typable by multiplex PCR and we also found sequence type of unknown type in thirteen isolates. The majority of <i>S. suis</i> isolates were resistant to clindamycin (n = 31), tetracycline (n = 29) and tilmicosin and tulathromycin (n = 28). On the other hand, with the exception of two isolates that were intermediately susceptible to penicillin and ampicillin, all isolates were susceptible to all three tested subgroups of beta-lactam antibiotics.https://www.mdpi.com/2076-0817/10/10/1314<i>Streptococcus suis</i>SPF farmserotypeMLSTantimicrobial susceptibilityantimicrobial treatment |
| spellingShingle | Ján Matiašovic Kateřina Nedbalcová Marek Žižlavský Petr Fleischer Lucie Pokludová Dita Kellnerová Kateřina Nechvátalová Bronislav Šimek Linda Czanderlová Monika Zouharová Jan Bernardy Natálie Králová Soňa Šlosárková <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms Pathogens <i>Streptococcus suis</i> SPF farm serotype MLST antimicrobial susceptibility antimicrobial treatment |
| title | <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms |
| title_full | <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms |
| title_fullStr | <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms |
| title_full_unstemmed | <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms |
| title_short | <i>Streptococcus suis</i> Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms |
| title_sort | i streptococcus suis i isolates serotypes and susceptibility to antimicrobials in terms of their use on selected repopulated czech pig farms |
| topic | <i>Streptococcus suis</i> SPF farm serotype MLST antimicrobial susceptibility antimicrobial treatment |
| url | https://www.mdpi.com/2076-0817/10/10/1314 |
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