Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia
Abstract We investigated changes in refraction and ocular biometrics in preschool children with early-onset high myopia. Sixty eyes of 60 children with a mean follow-up time of 58.5 months were included in this study. At baseline, mean age of children was 55.6 ± 13.1 months, mean spherical equivalen...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-50004-8 |
| _version_ | 1827399544263933952 |
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| author | Hae Ri Yum Shin Hae Park Sun Young Shin |
| author_facet | Hae Ri Yum Shin Hae Park Sun Young Shin |
| author_sort | Hae Ri Yum |
| collection | DOAJ |
| description | Abstract We investigated changes in refraction and ocular biometrics in preschool children with early-onset high myopia. Sixty eyes of 60 children with a mean follow-up time of 58.5 months were included in this study. At baseline, mean age of children was 55.6 ± 13.1 months, mean spherical equivalent (SE) was − 8.59 ± 2.66 D, and 25.64 ± 1.16 mm for axial length (AL). The total annual rate of myopic progression and axial elongation were − 0.37 ± 0.39 D/year and 0.33 ± 0.18 mm/year, respectively. During follow-up period, there was a trend toward less myopic progression and axial elongation over time. Of the total participants, 24 children (40%) were in the myopia progression group and the remaining 36 children (60%) were in the myopia stability group. In multiple linear regression analysis, baseline SE and AL were independently associated with myopic progression, while age, sex, and baseline AL-to-CR ratio were not related to myopic progression. According to the model, more myopic SE (β = − 0.186, P = 0.035) and longer AL (β = − 0.391, P = 0.008) at baseline were significantly associated with myopic progression. Myopia progression in preschoolers with high myopia tended to be relatively modest, with 60% of subjects exhibited myopic stability. Higher myopic SE, and longer AL at baseline were associated with myopic progression in preschool children with high myopia. |
| first_indexed | 2024-03-08T19:47:37Z |
| format | Article |
| id | doaj.art-a13339b1896c422b8ac45d49327f6ecf |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T19:47:37Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
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| spelling | doaj.art-a13339b1896c422b8ac45d49327f6ecf2023-12-24T12:17:12ZengNature PortfolioScientific Reports2045-23222023-12-011311610.1038/s41598-023-50004-8Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopiaHae Ri Yum0Shin Hae Park1Sun Young Shin2Department of Ophthalmology, College of Medicine, Eunpyeong St. Mary’s Hospital, The Catholic University of KoreaDepartment of Ophthalmology, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of KoreaDepartment of Ophthalmology, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of KoreaAbstract We investigated changes in refraction and ocular biometrics in preschool children with early-onset high myopia. Sixty eyes of 60 children with a mean follow-up time of 58.5 months were included in this study. At baseline, mean age of children was 55.6 ± 13.1 months, mean spherical equivalent (SE) was − 8.59 ± 2.66 D, and 25.64 ± 1.16 mm for axial length (AL). The total annual rate of myopic progression and axial elongation were − 0.37 ± 0.39 D/year and 0.33 ± 0.18 mm/year, respectively. During follow-up period, there was a trend toward less myopic progression and axial elongation over time. Of the total participants, 24 children (40%) were in the myopia progression group and the remaining 36 children (60%) were in the myopia stability group. In multiple linear regression analysis, baseline SE and AL were independently associated with myopic progression, while age, sex, and baseline AL-to-CR ratio were not related to myopic progression. According to the model, more myopic SE (β = − 0.186, P = 0.035) and longer AL (β = − 0.391, P = 0.008) at baseline were significantly associated with myopic progression. Myopia progression in preschoolers with high myopia tended to be relatively modest, with 60% of subjects exhibited myopic stability. Higher myopic SE, and longer AL at baseline were associated with myopic progression in preschool children with high myopia.https://doi.org/10.1038/s41598-023-50004-8 |
| spellingShingle | Hae Ri Yum Shin Hae Park Sun Young Shin Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia Scientific Reports |
| title | Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia |
| title_full | Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia |
| title_fullStr | Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia |
| title_full_unstemmed | Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia |
| title_short | Longitudinal analysis of refraction and ocular biometrics in preschool children with early-onset high myopia |
| title_sort | longitudinal analysis of refraction and ocular biometrics in preschool children with early onset high myopia |
| url | https://doi.org/10.1038/s41598-023-50004-8 |
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