Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines
ABSTRACTBackground Pharmacological management of fibromyalgia is complex. Chronic pain management is characterized by off-label prescribing and use, multimorbidity, and polypharmacy.Aims This study aimed to describe pain medications use and perceived risk among people living with fibromyalgia and co...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-07-01
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| Series: | Canadian Journal of Pain |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/24740527.2023.2252037 |
| _version_ | 1797352861533732864 |
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| author | Gwenaelle De Clifford-Faugère Hermine Lore Nguena Nguefack Marimée Godbout-Parent Mamadou Aliou Diallo Line Guénette M. Gabrielle Pagé Manon Choinière Sylvie Beaudoin Aline Boulanger Anne Marie Pinard David Lussier Philippe De Grandpré Simon Deslauriers Anaïs Lacasse |
| author_facet | Gwenaelle De Clifford-Faugère Hermine Lore Nguena Nguefack Marimée Godbout-Parent Mamadou Aliou Diallo Line Guénette M. Gabrielle Pagé Manon Choinière Sylvie Beaudoin Aline Boulanger Anne Marie Pinard David Lussier Philippe De Grandpré Simon Deslauriers Anaïs Lacasse |
| author_sort | Gwenaelle De Clifford-Faugère |
| collection | DOAJ |
| description | ABSTRACTBackground Pharmacological management of fibromyalgia is complex. Chronic pain management is characterized by off-label prescribing and use, multimorbidity, and polypharmacy.Aims This study aimed to describe pain medications use and perceived risk among people living with fibromyalgia and compare this use to evidence-based recommendations.Methods Directive telephone interviews were conducted with 63 individuals self-reporting a diagnosis of fibromyalgia (Quebec, Canada). The questionnaire addressed specific questions about their pain and pharmacological treatments currently used for pain management (prescribed and over-the-counter). Collected data were compared to the Canadian Fibromyalgia Clinical Practice Guidelines and to evidence reports published by recognized organizations.Results Despite a lack of robust scientific evidence to support opioids use to manage pain in fibromyalgia, 33% of our sample reported using them. Nonsteroidal anti-inflammatory drugs were used by 54.0% of participants, although this medication is not recommended due to lack of efficacy. Tramadol, which is recommended, was used by 23.8% of participants. Among the medications strongly recommended, anticonvulsants were used by 36.5%, serotonin norepinephrine reuptake inhibitor antidepressants by 55.6%, and tricyclic antidepressants by 22.2%. Cannabinoids (17.5%) and medical cannabis (34.9%) use were also reported. For all of these medication subclasses, no differences were found between participants not reporting (n = 35) or reporting (n = 28) more than one pain diagnosis (P < 0.05). Medication subclasses considered most at risk of adverse effects by participants were the least used.Conclusions Results reveal discordance between evidence-based recommendations and medications use, which highlights the complexity of pharmacological treatment of fibromyalgia. |
| first_indexed | 2024-03-08T13:22:50Z |
| format | Article |
| id | doaj.art-a1366b9d85b14f0c9198309cfc577570 |
| institution | Directory Open Access Journal |
| issn | 2474-0527 |
| language | English |
| last_indexed | 2024-03-08T13:22:50Z |
| publishDate | 2023-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Canadian Journal of Pain |
| spelling | doaj.art-a1366b9d85b14f0c9198309cfc5775702024-01-17T19:59:41ZengTaylor & Francis GroupCanadian Journal of Pain2474-05272023-07-017210.1080/24740527.2023.2252037Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice GuidelinesGwenaelle De Clifford-Faugère0Hermine Lore Nguena Nguefack1Marimée Godbout-Parent2Mamadou Aliou Diallo3Line Guénette4M. Gabrielle Pagé5Manon Choinière6Sylvie Beaudoin7Aline Boulanger8Anne Marie Pinard9David Lussier10Philippe De Grandpré11Simon Deslauriers12Anaïs Lacasse13Département des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), RouynNoranda, Québec, CanadaDépartement des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), RouynNoranda, Québec, CanadaDépartement des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), RouynNoranda, Québec, CanadaDépartement des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), RouynNoranda, Québec, CanadaCentre de recherche du Centre hospitalier universitaire de Québec–Université Laval, Quebec City, Québec, CanadaCentre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montréal, Québec, CanadaCentre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montréal, Québec, CanadaDépartement d’anesthésiologie et de médecine de la douleur, Faculté de médecine, Université de Montréal, Montréal, Québec, CanadaDépartement d’anesthésiologie et de médecine de la douleur, Faculté de médecine, Université de Montréal, Montréal, Québec, CanadaCentre d’expertise en gestion de la douleur chronique, Centre hospitalier de l’Université de Montréal, Montréal, Québec, CanadaInstitut universitaire de gériatrie de Montréal, Montréal, Québec, CanadaFamiliprix Chantale Gaboury & Marie-Ève Gélinas, Québec, CanadaVITAM–Centre de recherche en santé durable, CIUSSS de la CapitaleNationale, Quebec City, Québec, CanadaDépartement des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), RouynNoranda, Québec, CanadaABSTRACTBackground Pharmacological management of fibromyalgia is complex. Chronic pain management is characterized by off-label prescribing and use, multimorbidity, and polypharmacy.Aims This study aimed to describe pain medications use and perceived risk among people living with fibromyalgia and compare this use to evidence-based recommendations.Methods Directive telephone interviews were conducted with 63 individuals self-reporting a diagnosis of fibromyalgia (Quebec, Canada). The questionnaire addressed specific questions about their pain and pharmacological treatments currently used for pain management (prescribed and over-the-counter). Collected data were compared to the Canadian Fibromyalgia Clinical Practice Guidelines and to evidence reports published by recognized organizations.Results Despite a lack of robust scientific evidence to support opioids use to manage pain in fibromyalgia, 33% of our sample reported using them. Nonsteroidal anti-inflammatory drugs were used by 54.0% of participants, although this medication is not recommended due to lack of efficacy. Tramadol, which is recommended, was used by 23.8% of participants. Among the medications strongly recommended, anticonvulsants were used by 36.5%, serotonin norepinephrine reuptake inhibitor antidepressants by 55.6%, and tricyclic antidepressants by 22.2%. Cannabinoids (17.5%) and medical cannabis (34.9%) use were also reported. For all of these medication subclasses, no differences were found between participants not reporting (n = 35) or reporting (n = 28) more than one pain diagnosis (P < 0.05). Medication subclasses considered most at risk of adverse effects by participants were the least used.Conclusions Results reveal discordance between evidence-based recommendations and medications use, which highlights the complexity of pharmacological treatment of fibromyalgia.https://www.tandfonline.com/doi/10.1080/24740527.2023.2252037fibromyalgiapainmedicationsguidelinesriskperceived risk |
| spellingShingle | Gwenaelle De Clifford-Faugère Hermine Lore Nguena Nguefack Marimée Godbout-Parent Mamadou Aliou Diallo Line Guénette M. Gabrielle Pagé Manon Choinière Sylvie Beaudoin Aline Boulanger Anne Marie Pinard David Lussier Philippe De Grandpré Simon Deslauriers Anaïs Lacasse Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines Canadian Journal of Pain fibromyalgia pain medications guidelines risk perceived risk |
| title | Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines |
| title_full | Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines |
| title_fullStr | Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines |
| title_full_unstemmed | Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines |
| title_short | Pain Medications Used by Persons Living With Fibromyalgia: A Comparison Between the Profile of a Quebec Sample and Clinical Practice Guidelines |
| title_sort | pain medications used by persons living with fibromyalgia a comparison between the profile of a quebec sample and clinical practice guidelines |
| topic | fibromyalgia pain medications guidelines risk perceived risk |
| url | https://www.tandfonline.com/doi/10.1080/24740527.2023.2252037 |
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