Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

The SF-1 transcription factor target gene <i>FATE1</i> encodes a cancer-testis antigen that has an important role in regulating apoptosis and response to chemotherapy in adrenocortical carcinoma (ACC) cells. Autoantibodies directed against FATE1 were previously detected in patients with...

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Bibliographic Details
Main Authors: Mabrouka Doghman-Bouguerra, Pascal Finetti, Nelly Durand, Ivy Zortéa S. Parise, Silviu Sbiera, Giulia Cantini, Letizia Canu, Ségolène Hescot, Mirna M. O. Figueiredo, Heloisa Komechen, Iuliu Sbiera, Gabriella Nesi, Angelo Paci, Abir Al Ghuzlan, Daniel Birnbaum, Eric Baudin, Michaela Luconi, Martin Fassnacht, Bonald C. Figueiredo, François Bertucci, Enzo Lalli
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
adrenocortical carcinoma
cancer-testis antigens
autoantibodies
immune response
Online Access:https://www.mdpi.com/2072-6694/12/3/689

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