Ligand Binding Domain of Estrogen Receptor Alpha Preserve a Conserved Structural Architecture Similar to Bacterial Taxis Receptors

Ligand Binding Domain of Estrogen Receptor Alpha Preserve a Conserved Structural Architecture Similar to Bacterial Taxis Receptors

It remains a mystery why estrogen hormone receptors (ERs), which are highly specific toward its endogenous hormones, are responsive to chemically distinct exogenous agents. Does it indicate that ERs are environmentally regulated? Here, we speculate that ERs would have some common structural features...

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Bibliographic Details
Main Authors: Divya Lakshmanan Mangalath, Shabeer Ali Hassan Mohammed
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Ecology and Evolution
Subjects:
estrogen receptor
ligand binding domain
taxis receptors
domain architecture
nuclear hormone receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fevo.2021.681913/full

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