Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy
Enterovirus infection is endemic in many areas, especially in Southeast Asia. Enterovirus infection with severe complications (EVSC) is life-threatening, and timely diagnosis and management are crucial for successful management. Here, we report on a 2-year-old boy with hand, foot, and mouth disease....
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/5/643 |
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| author | Chien-Yu Lin Shih-Yu Huang Chuen-Bin Jiang Chun-Chih Peng Hsin Chi Nan-Chang Chiu |
| author_facet | Chien-Yu Lin Shih-Yu Huang Chuen-Bin Jiang Chun-Chih Peng Hsin Chi Nan-Chang Chiu |
| author_sort | Chien-Yu Lin |
| collection | DOAJ |
| description | Enterovirus infection is endemic in many areas, especially in Southeast Asia. Enterovirus infection with severe complications (EVSC) is life-threatening, and timely diagnosis and management are crucial for successful management. Here, we report on a 2-year-old boy with hand, foot, and mouth disease. Myoclonic jerks developed and left abducens nerve palsy followed. Brain magnetic resonance imaging (MRI) showed rhombencephalitis. Pulmonary edema and cardiopulmonary failure developed, and intravenous immunoglobulin and extracorporeal membrane oxygenation were administered. He had a tracheostomy with home ventilator use after 64 days of hospitalization. At a 5-year follow-up, his neurodevelopment was normal with complete recovery from the abducens nerve palsy. The progress of EVSC may be rapid and fulminant, and timely diagnosis is critical for patient prognosis and outcomes. The presence of abducens nerve palsy is an indicator of enteroviral rhombencephalitis, and immediate and appropriate management is suggested. |
| first_indexed | 2024-03-10T03:08:54Z |
| format | Article |
| id | doaj.art-a13ea816e79241eba73df70825f565e2 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-10T03:08:54Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-a13ea816e79241eba73df70825f565e22023-11-23T10:30:17ZengMDPI AGChildren2227-90672022-04-019564310.3390/children9050643Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old BoyChien-Yu Lin0Shih-Yu Huang1Chuen-Bin Jiang2Chun-Chih Peng3Hsin Chi4Nan-Chang Chiu5Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, TaiwanDepartment of Internal Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, TaiwanDepartment of Medicine, MacKay Medical College, New Taipei 25160, TaiwanDepartment of Medicine, MacKay Medical College, New Taipei 25160, TaiwanDepartment of Medicine, MacKay Medical College, New Taipei 25160, TaiwanDepartment of Medicine, MacKay Medical College, New Taipei 25160, TaiwanEnterovirus infection is endemic in many areas, especially in Southeast Asia. Enterovirus infection with severe complications (EVSC) is life-threatening, and timely diagnosis and management are crucial for successful management. Here, we report on a 2-year-old boy with hand, foot, and mouth disease. Myoclonic jerks developed and left abducens nerve palsy followed. Brain magnetic resonance imaging (MRI) showed rhombencephalitis. Pulmonary edema and cardiopulmonary failure developed, and intravenous immunoglobulin and extracorporeal membrane oxygenation were administered. He had a tracheostomy with home ventilator use after 64 days of hospitalization. At a 5-year follow-up, his neurodevelopment was normal with complete recovery from the abducens nerve palsy. The progress of EVSC may be rapid and fulminant, and timely diagnosis is critical for patient prognosis and outcomes. The presence of abducens nerve palsy is an indicator of enteroviral rhombencephalitis, and immediate and appropriate management is suggested.https://www.mdpi.com/2227-9067/9/5/643enterovirusrhombencephalitisbrainstem encephalitisenterovirus infection with severe complicationsintravenous immunoglobulinextracorporeal membrane oxygenation |
| spellingShingle | Chien-Yu Lin Shih-Yu Huang Chuen-Bin Jiang Chun-Chih Peng Hsin Chi Nan-Chang Chiu Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy Children enterovirus rhombencephalitis brainstem encephalitis enterovirus infection with severe complications intravenous immunoglobulin extracorporeal membrane oxygenation |
| title | Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy |
| title_full | Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy |
| title_fullStr | Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy |
| title_full_unstemmed | Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy |
| title_short | Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy |
| title_sort | enteroviral rhombencephalitis with abducens nerve palsy and cardio pulmonary failure in a 2 year old boy |
| topic | enterovirus rhombencephalitis brainstem encephalitis enterovirus infection with severe complications intravenous immunoglobulin extracorporeal membrane oxygenation |
| url | https://www.mdpi.com/2227-9067/9/5/643 |
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