Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models

The purpose of this study is to assess clinical, MR, USG and histopathological findings of early and later results of polyester film use in experimental ventral hernia model in rabbits. In this study, 16 New Zealand rabbits were divided into 2 groups of 8 rabbits each. After xylazine HCl usage as a...

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Main Authors: Engin KILIÇ, Sadık YAYLA, Vedat BARAN, Berna Ersöz KANAY, Celal Şahin ERMUTLU, Kemal KILIÇ, Mustafa GÖK, Serpil DAĞ
Format: Article
Language:English
Published: Kafkas University, Faculty of Veterinary Medicine 2019-03-01
Series:Kafkas Universitesi Veteriner Fakültesi Dergisi
Subjects:
Online Access:https://vetdergikafkas.org/pdf.php?id=2497
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author Engin KILIÇ
Sadık YAYLA
Vedat BARAN
Berna Ersöz KANAY
Celal Şahin ERMUTLU
Kemal KILIÇ
Mustafa GÖK
Serpil DAĞ
author_facet Engin KILIÇ
Sadık YAYLA
Vedat BARAN
Berna Ersöz KANAY
Celal Şahin ERMUTLU
Kemal KILIÇ
Mustafa GÖK
Serpil DAĞ
author_sort Engin KILIÇ
collection DOAJ
description The purpose of this study is to assess clinical, MR, USG and histopathological findings of early and later results of polyester film use in experimental ventral hernia model in rabbits. In this study, 16 New Zealand rabbits were divided into 2 groups of 8 rabbits each. After xylazine HCl usage as a sedative, the surgery is conducted under general anaesthesia by ketamine HCl. Upon median skin incision, a 2 cm diameter round defect on linea alba level was formed in rabbits lying in the supine position. The defect was repaired with 4 cm diameter polyester film which had been prepared beforehand in the shape of a disc. After clinical follow up of 15 days for rabbits in group I and 60 days for group II, USG and MR images were taken, by re-laparotomy the presence and extent of peritoneal adhesion was examined visually. All data from the study were statistically assessed via Minitab-16 package program. Tissue samples from the graft area were stained through hematoxylineozin and Crossman"s triple dye and assessed by usage of light microscope. During histopathological examination, it was observed repair by fibrous tissue in the area where surgery was performed for all the animals in 15 day group. Neither foreign body giant cell reaction nor necrosis was observed in two groups. When clinical, USG, MR findings along with re-laparotomy, macroscopic and histopathological results are taken into account, it was seen that polyester film bore successful results with regards to ventral hernia therapy in rabbits. Based on the data provided by this study, it is decided that the mentioned material should be tried for large hernia defect repair in domestic animals.
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spelling doaj.art-a13f174911f742a7afecea4e66d73f8c2023-06-19T06:34:21ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512019-03-0125455956510.9775/kvfd.2018.213222497Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit modelsEngin KILIÇ0Sadık YAYLA1Vedat BARAN2Berna Ersöz KANAY3Celal Şahin ERMUTLU4Kemal KILIÇ5Mustafa GÖK6Serpil DAĞ7Kafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYDicle University, Faculty of Veterinary Medicine, Department of Surgery, TR-21280 Diyarbakır - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Surgery, TR-36100 Kars - TURKEYTuzla State Hospital, Clinic of General Surgery, TR-34947 İstanbul - TURKEYAdnan Menderes University, Faculty of Medicine, Department of Radiology, TR-09010 Aydın - TURKEYKafkas University, Faculty of Veterinary Medicine, Department of Pathology, TR-36100 Kars - TURKEYThe purpose of this study is to assess clinical, MR, USG and histopathological findings of early and later results of polyester film use in experimental ventral hernia model in rabbits. In this study, 16 New Zealand rabbits were divided into 2 groups of 8 rabbits each. After xylazine HCl usage as a sedative, the surgery is conducted under general anaesthesia by ketamine HCl. Upon median skin incision, a 2 cm diameter round defect on linea alba level was formed in rabbits lying in the supine position. The defect was repaired with 4 cm diameter polyester film which had been prepared beforehand in the shape of a disc. After clinical follow up of 15 days for rabbits in group I and 60 days for group II, USG and MR images were taken, by re-laparotomy the presence and extent of peritoneal adhesion was examined visually. All data from the study were statistically assessed via Minitab-16 package program. Tissue samples from the graft area were stained through hematoxylineozin and Crossman"s triple dye and assessed by usage of light microscope. During histopathological examination, it was observed repair by fibrous tissue in the area where surgery was performed for all the animals in 15 day group. Neither foreign body giant cell reaction nor necrosis was observed in two groups. When clinical, USG, MR findings along with re-laparotomy, macroscopic and histopathological results are taken into account, it was seen that polyester film bore successful results with regards to ventral hernia therapy in rabbits. Based on the data provided by this study, it is decided that the mentioned material should be tried for large hernia defect repair in domestic animals.https://vetdergikafkas.org/pdf.php?id=2497graftventral hernia repairpolyester filmrabbit
spellingShingle Engin KILIÇ
Sadık YAYLA
Vedat BARAN
Berna Ersöz KANAY
Celal Şahin ERMUTLU
Kemal KILIÇ
Mustafa GÖK
Serpil DAĞ
Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
Kafkas Universitesi Veteriner Fakültesi Dergisi
graft
ventral hernia repair
polyester film
rabbit
title Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
title_full Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
title_fullStr Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
title_full_unstemmed Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
title_short Evaluation of early and late period results of polyester film use for the repair of ventral hernias: an experimental study on rabbit models
title_sort evaluation of early and late period results of polyester film use for the repair of ventral hernias an experimental study on rabbit models
topic graft
ventral hernia repair
polyester film
rabbit
url https://vetdergikafkas.org/pdf.php?id=2497
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