Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis
Background: The septate uterus is the most common congenital uterine anomaly, and hysteroscopy is the gold standard for diagnosing it. The goal of this meta-analysis is to perform a pooled analysis of the diagnostic performance of two-dimensional transvaginal ultrasonography, two-dimensional transva...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/4/807 |
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| author | Juan Luis Alcázar Isabel Carriles María Belén Cajas Susana Costa Sofia Fabra Maria Cabrero Elena Castro Aida Tomaizeh María Victoria Laza Alba Monroy Irene Martinez Maria Isabel Aguilar Elena Hernani Cristina Castellet Agustin Oliva María Ángela Pascual Stefano Guerriero |
| author_facet | Juan Luis Alcázar Isabel Carriles María Belén Cajas Susana Costa Sofia Fabra Maria Cabrero Elena Castro Aida Tomaizeh María Victoria Laza Alba Monroy Irene Martinez Maria Isabel Aguilar Elena Hernani Cristina Castellet Agustin Oliva María Ángela Pascual Stefano Guerriero |
| author_sort | Juan Luis Alcázar |
| collection | DOAJ |
| description | Background: The septate uterus is the most common congenital uterine anomaly, and hysteroscopy is the gold standard for diagnosing it. The goal of this meta-analysis is to perform a pooled analysis of the diagnostic performance of two-dimensional transvaginal ultrasonography, two-dimensional transvaginal sonohysterography, three-dimensional transvaginal ultrasound, and three-dimensional transvaginal sonohysterography for the diagnosis of the septate uterus. Methods: Studies published between 1990 and 2022 were searched in PubMed, Scopus, and Web of Science. From 897 citations, we selected eighteen studies to include in this meta-analysis. Results: The mean prevalence of uterine septum in this meta-analysis was 27.8%. Pooled sensitivity and specificity were 83% and 99% for two-dimensional transvaginal ultrasonography (ten studies), 94% and 100% for two-dimensional transvaginal sonohysterography (eight studies), and 98% and 100% for three-dimensional transvaginal ultrasound (seven articles), respectively. The diagnostic accuracy of three-dimensional transvaginal sonohysterography was only described in two studies, and we did not calculate the pooled sensitivity and specificity for this method. Conclusion: Three-dimensional transvaginal ultrasound has the best performance capacity for the diagnosis of the septate uterus. |
| first_indexed | 2024-03-11T08:57:11Z |
| format | Article |
| id | doaj.art-a143a012a1d24d268c68c83add30d213 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T08:57:11Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-a143a012a1d24d268c68c83add30d2132023-11-16T20:03:16ZengMDPI AGDiagnostics2075-44182023-02-0113480710.3390/diagnostics13040807Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-AnalysisJuan Luis Alcázar0Isabel Carriles1María Belén Cajas2Susana Costa3Sofia Fabra4Maria Cabrero5Elena Castro6Aida Tomaizeh7María Victoria Laza8Alba Monroy9Irene Martinez10Maria Isabel Aguilar11Elena Hernani12Cristina Castellet13Agustin Oliva14María Ángela Pascual15Stefano Guerriero16Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, SpainDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario de Salamanca, 37007 Salamanca, SpainDepartment Obstetrics and Gynecology, Centro Hospitalar e Universitário de São João, 4200-319 Porto, PortugalDepartment of Obstetrics and Gynecology, Hospital Universitario Infanta Sofia, 28702 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario de Salamanca, 37007 Salamanca, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Virgen de la Arrixaca, 30120 Murcia, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Virgen de Valme, 41701 Sevilla, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Materno-Infantil, 06010 Badajoz, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Materno-Infantil, 06010 Badajoz, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Virgen de Valme, 41701 Sevilla, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario Virgen de Valme, 41701 Sevilla, SpainDepartment of Obstetrics and Gynecology, Hospital General Universitario de Castellón, 12004 Castellón, SpainDepartment of Obstetrics, Gynecology, and Reproduction, Hospital Universitari Dexeus, 08028 Barcelona, SpainDepartment of Obstetrics and Gynecology, Hospital Universitario San Carlos, 28040 Madrid, SpainDepartment of Obstetrics, Gynecology, and Reproduction, Hospital Universitari Dexeus, 08028 Barcelona, SpainCentro Integrato di Procreazione Medicalmente Assistita (PMA) e Diagnostica Ostetrico-Ginecologica, Azienda Ospedaliero Universitaria-Policlinico Duilio Casula, Monserrato, 09042 Cagliari, ItalyBackground: The septate uterus is the most common congenital uterine anomaly, and hysteroscopy is the gold standard for diagnosing it. The goal of this meta-analysis is to perform a pooled analysis of the diagnostic performance of two-dimensional transvaginal ultrasonography, two-dimensional transvaginal sonohysterography, three-dimensional transvaginal ultrasound, and three-dimensional transvaginal sonohysterography for the diagnosis of the septate uterus. Methods: Studies published between 1990 and 2022 were searched in PubMed, Scopus, and Web of Science. From 897 citations, we selected eighteen studies to include in this meta-analysis. Results: The mean prevalence of uterine septum in this meta-analysis was 27.8%. Pooled sensitivity and specificity were 83% and 99% for two-dimensional transvaginal ultrasonography (ten studies), 94% and 100% for two-dimensional transvaginal sonohysterography (eight studies), and 98% and 100% for three-dimensional transvaginal ultrasound (seven articles), respectively. The diagnostic accuracy of three-dimensional transvaginal sonohysterography was only described in two studies, and we did not calculate the pooled sensitivity and specificity for this method. Conclusion: Three-dimensional transvaginal ultrasound has the best performance capacity for the diagnosis of the septate uterus.https://www.mdpi.com/2075-4418/13/4/807ultrasoundsonohysterographyseptate uterusmullerian anomalies |
| spellingShingle | Juan Luis Alcázar Isabel Carriles María Belén Cajas Susana Costa Sofia Fabra Maria Cabrero Elena Castro Aida Tomaizeh María Victoria Laza Alba Monroy Irene Martinez Maria Isabel Aguilar Elena Hernani Cristina Castellet Agustin Oliva María Ángela Pascual Stefano Guerriero Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis Diagnostics ultrasound sonohysterography septate uterus mullerian anomalies |
| title | Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis |
| title_full | Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis |
| title_fullStr | Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis |
| title_short | Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus—A Systematic Review and Meta-Analysis |
| title_sort | diagnostic performance of two dimensional ultrasound two dimensional sonohysterography and three dimensional ultrasound in the diagnosis of septate uterus a systematic review and meta analysis |
| topic | ultrasound sonohysterography septate uterus mullerian anomalies |
| url | https://www.mdpi.com/2075-4418/13/4/807 |
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