Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

A number of pyrrolo[2,3-<i>c</i>]pyridines, pyrrolo[3,2-<i>d</i>]pyrimidines and pyrazolo[4,3-<i>d</i>]pyrimidines were designed and synthesized as antiproliferative agents. The target compounds possessed selected substituents in analogous positions on the central...

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Những tác giả chính: Spyridon Dimitrakis, Efthymios-Spyridon Gavriil, Athanasios Pousias, Nikolaos Lougiakis, Panagiotis Marakos, Nicole Pouli, Katerina Gioti, Roxane Tenta
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2021-12-01
Loạt:Molecules
Những chủ đề:
purine isosteres
pyrrolopyridine
pyrrolopyrimidine
pyrazolopyrimidine
synthesis
cytotoxic activity
Truy cập trực tuyến:https://www.mdpi.com/1420-3049/27/1/247

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https://www.mdpi.com/1420-3049/27/1/247

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