Conidial dihydroxynaphthalene melanin of the human pathogenic fungus Aspergillus fumigatus interferes with the host endocytosis pathway

Conidial dihydroxynaphthalene melanin of the human pathogenic fungus Aspergillus fumigatus interferes with the host endocytosis pathway

Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The interaction of the pathogen with the host’s immune system represents a key process to understand pathogenicity. For elimination of invading microorganisms, they need to be efficiently phagocytosed and located in aci...

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Bibliographic Details
Main Authors: Andreas eThywißen, Thorsten eHeinekamp, Hans-Martin eDahse, Jeannette eSchmaler-Ripcke, Sandor eNietsche, Peter F. Zipfel, Axel A Brakhage
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus fumigatus
Endocytosis
Macrophages
Neutrophils
Virulence
melanin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00096/full

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