The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants
The last ten years have seen rapid strides in the evolution of nonvitamin K oral anticoagulants (NOACs) for stroke prevention in patients with atrial fibrillation (AF). For the preparation of this consensus, a comprehensive literature search was performed and data on available trials, subpopulation...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-12-01
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| Series: | Indian Heart Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483215008251 |
| _version_ | 1819172003087646720 |
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| author | Jamshed Dalal Abhay Bhave Abraham Oomman Amit Vora Anil Saxena Dhiman Kahali Fali Poncha D.S. Gambhir Jaydip Ray Chaudhuri Nakul Sinha Saumitra Ray S.S. Iyengar Suvro Banerjee Upendra Kaul |
| author_facet | Jamshed Dalal Abhay Bhave Abraham Oomman Amit Vora Anil Saxena Dhiman Kahali Fali Poncha D.S. Gambhir Jaydip Ray Chaudhuri Nakul Sinha Saumitra Ray S.S. Iyengar Suvro Banerjee Upendra Kaul |
| author_sort | Jamshed Dalal |
| collection | DOAJ |
| description | The last ten years have seen rapid strides in the evolution of nonvitamin K oral anticoagulants (NOACs) for stroke prevention in patients with atrial fibrillation (AF). For the preparation of this consensus, a comprehensive literature search was performed and data on available trials, subpopulation analyses, and case reports were analyzed. This Indian consensus document intends to provide guidance on selecting the right NOAC for the right patients by formulating expert opinions based on the available trials and Asian/Indian subpopulation analyses of these trials. A section has been dedicated to the current evidence of NOACs in the Asian population. Practical suggestions have been formulated in the following clinical situations: (i) Dose recommendations of the NOACs in different clinical scenarios; (ii) NOACs in patients with rheumatic heart disease (RHD); (iii) Monitoring anticoagulant effect of the NOACs; (iv) Overdose of NOACs; (v) Antidotes to NOACs; (vi) Treatment of hypertrophic cardiomyopathy (HCM) with AF using NOACs; (vii) NOACs dose in elderly, (viii) Switching between NOACs and vitamin K antagonists (VKA); (ix) Cardioversion or ablation in NOAC-treated patients; (x) Planned/emergency surgical interventions in patients currently on NOACs; (xi) Management of bleeding complications of NOACs; (xii) Management of acute coronary syndrome (ACS) in AF with NOACs; (xiii) Management of acute ischemic stroke while on NOACs. |
| first_indexed | 2024-12-22T20:00:16Z |
| format | Article |
| id | doaj.art-a14bd5f2a5744fb4b7d7a2f9edbdf3e1 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-22T20:00:16Z |
| publishDate | 2015-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-a14bd5f2a5744fb4b7d7a2f9edbdf3e12022-12-21T18:14:17ZengElsevierIndian Heart Journal0019-48322015-12-0167S2S13S3410.1016/j.ihj.2015.10.380The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulantsJamshed Dalal0Abhay Bhave1Abraham Oomman2Amit Vora3Anil Saxena4Dhiman Kahali5Fali Poncha6D.S. Gambhir7Jaydip Ray Chaudhuri8Nakul Sinha9Saumitra Ray10S.S. Iyengar11Suvro Banerjee12Upendra Kaul13Director, Centre for Cardiac Sciences, Kokilaben Dhirubhai Ambani Hospital, Mumbai, IndiaHon. Consultant Haematologist, Lilavati Hospital and Research Centre, Mumbai, IndiaSr Consultant Cardiologist, Apollo Hospital, Chennai, IndiaElectrophysiologist, Arrhythmia Associates and Glenmark Cardiac Centre, Mumbai, IndiaDirector, Cardiac Pacing and Electrophysiology, Fortis Escorts Heart Institute, New Delhi, IndiaSr Consultant Interventional Cardiologist, BM Birla Heart Research Centre, Kolkata, IndiaConsultant Neurologist, Jaslok Hospital, Mumbai, IndiaGroup Director, Cardiology, Kailash Group of Hospitals and Heart Institute, Noida, IndiaHOD, Neurology, Yashoda Hospital, Hyderabad, IndiaSr Consultant and Chief Interventional Cardiologist, Sahara Hospital, Lucknow, IndiaConsultant Interventional Cardiologist, AMRI Hospital, Kolkata, IndiaConsultant and HOD-Cardiology, Manipal Hospitals, Bengaluru, IndiaConsultant Interventional Cardiologist at Apollo Gleneagles Hospital, Kolkata, IndiaProfessor Cardiology, AIIMS, AIIM International and Executive Director and Dean Fortis Escorts Heart Institute, New Delhi, IndiaThe last ten years have seen rapid strides in the evolution of nonvitamin K oral anticoagulants (NOACs) for stroke prevention in patients with atrial fibrillation (AF). For the preparation of this consensus, a comprehensive literature search was performed and data on available trials, subpopulation analyses, and case reports were analyzed. This Indian consensus document intends to provide guidance on selecting the right NOAC for the right patients by formulating expert opinions based on the available trials and Asian/Indian subpopulation analyses of these trials. A section has been dedicated to the current evidence of NOACs in the Asian population. Practical suggestions have been formulated in the following clinical situations: (i) Dose recommendations of the NOACs in different clinical scenarios; (ii) NOACs in patients with rheumatic heart disease (RHD); (iii) Monitoring anticoagulant effect of the NOACs; (iv) Overdose of NOACs; (v) Antidotes to NOACs; (vi) Treatment of hypertrophic cardiomyopathy (HCM) with AF using NOACs; (vii) NOACs dose in elderly, (viii) Switching between NOACs and vitamin K antagonists (VKA); (ix) Cardioversion or ablation in NOAC-treated patients; (x) Planned/emergency surgical interventions in patients currently on NOACs; (xi) Management of bleeding complications of NOACs; (xii) Management of acute coronary syndrome (ACS) in AF with NOACs; (xiii) Management of acute ischemic stroke while on NOACs.http://www.sciencedirect.com/science/article/pii/S0019483215008251AFSPAFDabigatranRivaroxabanApixaban |
| spellingShingle | Jamshed Dalal Abhay Bhave Abraham Oomman Amit Vora Anil Saxena Dhiman Kahali Fali Poncha D.S. Gambhir Jaydip Ray Chaudhuri Nakul Sinha Saumitra Ray S.S. Iyengar Suvro Banerjee Upendra Kaul The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants Indian Heart Journal AF SPAF Dabigatran Rivaroxaban Apixaban |
| title | The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants |
| title_full | The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants |
| title_fullStr | The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants |
| title_full_unstemmed | The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants |
| title_short | The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants |
| title_sort | indian consensus guidance on stroke prevention in atrial fibrillation an emphasis on practical use of nonvitamin k oral anticoagulants |
| topic | AF SPAF Dabigatran Rivaroxaban Apixaban |
| url | http://www.sciencedirect.com/science/article/pii/S0019483215008251 |
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