Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty
We developed a computerized clinical decision support system (CCDSS) for venous thromboembolism (VTE) risk assessment. We aimed to demonstrate its relevance and evaluate associations between risk level and VTE incidence in patients undergoing total hip/knee arthroplasty. In this case-control study,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-05-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296221103868 |
| _version_ | 1811239654916096000 |
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| author | Akihiko Akamine MSc Naonobu Takahira PhD Masayuki Kuroiwa PhD Atsushi Tomizawa MSc Koichiro Atsuda PhD |
| author_facet | Akihiko Akamine MSc Naonobu Takahira PhD Masayuki Kuroiwa PhD Atsushi Tomizawa MSc Koichiro Atsuda PhD |
| author_sort | Akihiko Akamine MSc |
| collection | DOAJ |
| description | We developed a computerized clinical decision support system (CCDSS) for venous thromboembolism (VTE) risk assessment. We aimed to demonstrate its relevance and evaluate associations between risk level and VTE incidence in patients undergoing total hip/knee arthroplasty. In this case-control study, VTE was confirmed using ultrasonography/computed tomography angiography in 1098 adults at a tertiary care hospital over five years (2013-2018). Postoperative VTE incidence was classified into three risk levels (moderate, high, and highest). The overall VTE incidence was 11.7%, which increased with a risk level of 0%, 5.8%, and 12.8% in moderate-risk, high-risk, and highest-risk patients, respectively. Highest-risk patients were significantly more likely to develop VTE than high-risk patients (odds ratio [OR] 2.4; 95% confidence interval [CI] 1.2-5.5; p = 0.01). VTE development was more likely in patients with risk scores ≥4 relative to those with risk scores of 2–3 (OR 1.8; 95% CI 1.2-2.7; p = 0.003) and −1 to 1 (OR 3.3; 95% CI 1.6-7.7; p < 0.001). This study indicates that risk level and VTE incidence are associated; our scoring system appears useful for patients undergoing total hip/knee arthroplasty. |
| first_indexed | 2024-04-12T13:03:46Z |
| format | Article |
| id | doaj.art-a15106c6221244e5a2e7f3bd065acddf |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-04-12T13:03:46Z |
| publishDate | 2022-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-a15106c6221244e5a2e7f3bd065acddf2022-12-22T03:32:05ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232022-05-012810.1177/10760296221103868Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee ArthroplastyAkihiko Akamine MSc0Naonobu Takahira PhD1Masayuki Kuroiwa PhD2Atsushi Tomizawa MSc3Koichiro Atsuda PhD4 Department of Pharmacy, , Sagamihara, Kanagawa, Japan Physical Therapy Course, Department of Rehabilitation, , Sagamihara, Kanagawa, Japan Department of Anesthesiology, , Sagamihara, Kanagawa 252-0373, Japan Department of Pharmacy, , Sagamihara, Kanagawa, Japan Research and Education Center for Clinical Pharmacy, Division of Clinical Pharmacy, Laboratory of Pharmacy Practice and Science 1, , Minato-ku, Tokyo, JapanWe developed a computerized clinical decision support system (CCDSS) for venous thromboembolism (VTE) risk assessment. We aimed to demonstrate its relevance and evaluate associations between risk level and VTE incidence in patients undergoing total hip/knee arthroplasty. In this case-control study, VTE was confirmed using ultrasonography/computed tomography angiography in 1098 adults at a tertiary care hospital over five years (2013-2018). Postoperative VTE incidence was classified into three risk levels (moderate, high, and highest). The overall VTE incidence was 11.7%, which increased with a risk level of 0%, 5.8%, and 12.8% in moderate-risk, high-risk, and highest-risk patients, respectively. Highest-risk patients were significantly more likely to develop VTE than high-risk patients (odds ratio [OR] 2.4; 95% confidence interval [CI] 1.2-5.5; p = 0.01). VTE development was more likely in patients with risk scores ≥4 relative to those with risk scores of 2–3 (OR 1.8; 95% CI 1.2-2.7; p = 0.003) and −1 to 1 (OR 3.3; 95% CI 1.6-7.7; p < 0.001). This study indicates that risk level and VTE incidence are associated; our scoring system appears useful for patients undergoing total hip/knee arthroplasty.https://doi.org/10.1177/10760296221103868 |
| spellingShingle | Akihiko Akamine MSc Naonobu Takahira PhD Masayuki Kuroiwa PhD Atsushi Tomizawa MSc Koichiro Atsuda PhD Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty Clinical and Applied Thrombosis/Hemostasis |
| title | Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty |
| title_full | Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty |
| title_fullStr | Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty |
| title_full_unstemmed | Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty |
| title_short | Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty |
| title_sort | internal validation of a risk scoring system for venous thromboembolism after total hip or knee arthroplasty |
| url | https://doi.org/10.1177/10760296221103868 |
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