THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS
Abstract Several non-thyroid factors such as age, breed, concomitant diseases and use of certain drugs might influence the diagnosis of hypothyroidism in dogs. Changes in the concentrations of thyroid hormones due to non-thyroid illnesses are named euthyroid sick syndrome. The aim of this study was...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Goiás
2016-04-01
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| Series: | Ciência Animal Brasileira |
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| Online Access: | https://revistas.ufg.br/vet/article/view/30979 |
| _version_ | 1797793048710610944 |
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| author | Mauro Jose Lahm Cardoso Maira Melussi Rafael Fagnani Luciane Holsback Thais Helena Patelli Eunice Oba |
| author_facet | Mauro Jose Lahm Cardoso Maira Melussi Rafael Fagnani Luciane Holsback Thais Helena Patelli Eunice Oba |
| author_sort | Mauro Jose Lahm Cardoso |
| collection | DOAJ |
| description |
Abstract
Several non-thyroid factors such as age, breed, concomitant diseases and use of certain drugs might influence the diagnosis of hypothyroidism in dogs. Changes in the concentrations of thyroid hormones due to non-thyroid illnesses are named euthyroid sick syndrome. The aim of this study was to evaluate the influence of visceral leishmaniasis on thyroid function in dogs without clinical signs of hypothyroidism, with or without azotemia. Positive animals for leishmaniasis were divided into six groups (absence or presence of hypoalbuminemia, normal or increased creatinine, normal or increased urea). The effect on these groups was evaluated on the thyroid-stimulating hormone (TSH), total thyroxine (TT4) and free thyroxine (FT4) concentrations. Dogs that were positive for leishmaniasis, by ELISA test, presented thyroid-stimulating hormone serum concentrations greater than seronegative animals, while total thyroxine and free thyroxine in dogs with leishmanisis were lower (P?0.01) when compared to healthy dogs. However, the results were within the values for euthyroid animals. In seropositive dogs for leishmaniasis, TT4 showed statistically significant difference (P?0.04) in the group with hypoalbuminemia compared to the group with normoalbuminemia, respectively, 1,01ug/dL and 1.4 g/dL. Based on this study, we could conclude that positive dogs for visceral leishmaniasis have not presented euthyroid sick syndrome, although when compared to healthy dogs, FT4 and TT4 were reduced and TSH increased.
Keywords: euthyroid; hypothyroidism; leishmania; sick syndrome; thyroxine.
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| first_indexed | 2024-03-13T02:42:39Z |
| format | Article |
| id | doaj.art-a157898810bc4420bfd2fb7b3ee8e196 |
| institution | Directory Open Access Journal |
| issn | 1518-2797 1809-6891 |
| language | English |
| last_indexed | 2024-03-13T02:42:39Z |
| publishDate | 2016-04-01 |
| publisher | Universidade Federal de Goiás |
| record_format | Article |
| series | Ciência Animal Brasileira |
| spelling | doaj.art-a157898810bc4420bfd2fb7b3ee8e1962023-06-28T21:09:25ZengUniversidade Federal de GoiásCiência Animal Brasileira1518-27971809-68912016-04-0117210.1590/cab17230979THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASISMauro Jose Lahm Cardoso0Maira Melussi1Rafael Fagnani2Luciane Holsback3Thais Helena Patelli4Eunice Oba5Universidade Estadual do Norte do ParanáEspaço Vida VeterináriaUniversidade do Norte do ParanáUniversidade Estadual do Norte do ParanáUniversidade Estadual do Norte do ParanáUNESP Abstract Several non-thyroid factors such as age, breed, concomitant diseases and use of certain drugs might influence the diagnosis of hypothyroidism in dogs. Changes in the concentrations of thyroid hormones due to non-thyroid illnesses are named euthyroid sick syndrome. The aim of this study was to evaluate the influence of visceral leishmaniasis on thyroid function in dogs without clinical signs of hypothyroidism, with or without azotemia. Positive animals for leishmaniasis were divided into six groups (absence or presence of hypoalbuminemia, normal or increased creatinine, normal or increased urea). The effect on these groups was evaluated on the thyroid-stimulating hormone (TSH), total thyroxine (TT4) and free thyroxine (FT4) concentrations. Dogs that were positive for leishmaniasis, by ELISA test, presented thyroid-stimulating hormone serum concentrations greater than seronegative animals, while total thyroxine and free thyroxine in dogs with leishmanisis were lower (P?0.01) when compared to healthy dogs. However, the results were within the values for euthyroid animals. In seropositive dogs for leishmaniasis, TT4 showed statistically significant difference (P?0.04) in the group with hypoalbuminemia compared to the group with normoalbuminemia, respectively, 1,01ug/dL and 1.4 g/dL. Based on this study, we could conclude that positive dogs for visceral leishmaniasis have not presented euthyroid sick syndrome, although when compared to healthy dogs, FT4 and TT4 were reduced and TSH increased. Keywords: euthyroid; hypothyroidism; leishmania; sick syndrome; thyroxine. https://revistas.ufg.br/vet/article/view/30979euthyroidsick syndromeleishmaniahypthyroidismthyroxine |
| spellingShingle | Mauro Jose Lahm Cardoso Maira Melussi Rafael Fagnani Luciane Holsback Thais Helena Patelli Eunice Oba THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS Ciência Animal Brasileira euthyroid sick syndrome leishmania hypthyroidism thyroxine |
| title | THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS |
| title_full | THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS |
| title_fullStr | THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS |
| title_full_unstemmed | THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS |
| title_short | THYROID FUNCTION IN DOGS WITH VISCERAL LEISHMANIASIS |
| title_sort | thyroid function in dogs with visceral leishmaniasis |
| topic | euthyroid sick syndrome leishmania hypthyroidism thyroxine |
| url | https://revistas.ufg.br/vet/article/view/30979 |
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