DYNAMIC cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults

DYNAMIC cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults

Abstract Immunosenescence (age-related immune dysfunction) and inflamm-aging contribute to suboptimal immune responses in older adults to standard-dose influenza vaccines, which may be exacerbated in those with metabolic co-morbidities. We sought to investigate metabolic factors/predictors of influe...

Full description

Bibliographic Details
Main Authors:	Sapna P. Sadarangani, Barnaby E. Young, Weixiang Lian, Hwee Pin Phua, Mark I.-C. Chen, Ian Barr, Tsin Wen Yeo, Rinkoo Dalan, Angela Chow
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-11-01
Series:	npj Vaccines
Online Access:	https://doi.org/10.1038/s41541-022-00548-z

Similar Items

Dynamic cohort study evaluating metabolic predictors of influenza vaccine immune response in older adults
by: Sadarangani, Sapna, et al.
Published: (2023)

Duration of Influenza Vaccine Effectiveness: A Systematic Review, Meta-analysis, and Meta-regression of Test-Negative Design Case-Control Studies
by: Young, Barnaby, et al.
Published: (2018)

The immune response to 6-monthly versus annual standard dose inactivated trivalent influenza vaccination in older people: study protocol for a randomised clinical trial
by: Young, Barnaby, et al.
Published: (2017)

Carotid atherosclerosis : an ultrasonographic window for subclinical atherosclerotic cardiovascular disease
by: Dalan, Rinkoo
Published: (2024)

Proof-of-concept study for an enhanced surrogate marker of endothelial function in diabetes
by: Goh, S., et al.
Published: (2018)

Pre-operative Serum Alkaline Phosphatase as a Predictor for Hypocalcemia Post-Parathyroid Adenectomy
by: Seng Cheong Loke, Alvin Wai Kit Tan, Rinkoo Dalan, Melvin Khee-Shing Leow
Published: (2012-01-01)

Novel Therapeutics for Type 2 Diabetes Mellitus—A Look at the Past Decade and a Glimpse into the Future
by: Ying Jie Chee, et al.
Published: (2024-06-01)

New Technologies for Influenza Vaccines
by: Steven Rockman, et al.
Published: (2020-11-01)

Adipsic Diabetes Insipidus—The Challenging Combination of Polyuria and Adipsia: A Case Report and Review of Literature
by: Rinkoo Dalan, et al.
Published: (2019-09-01)

Sex Modifies the Association of Fibroblast Growth Factor 21 With Subclinical Carotid Atherosclerosis
by: Yingjie Chee, et al.
Published: (2021-04-01)

Predictors of influenza among older adults in the emergency department
by: Po-Po Lam, et al.
Published: (2016-10-01)

Improving seasonal influenza vaccination for older adults
by: Graham Pawelec, et al.
Published: (2021-03-01)

Economic analysis of pandemic influenza vaccination strategies in Singapore.
by: Vernon J Lee, et al.
Published: (2009-01-01)

Effectiveness of the Adjuvanted Influenza Vaccine in Older Adults at High Risk of Influenza Complications
by: Constantina Boikos, et al.
Published: (2021-08-01)

Cushing’s Disease Management: Glimpse Into 2051
by: Rinkoo Dalan, et al.
Published: (2022-07-01)

Estimation of influenza vaccine effectiveness from routine surveillance data.
by: Heath Kelly, et al.
Published: (2009-01-01)

Predictor Factors Affecting Seroconversion Post-Influenza Vaccination in the Elderly
by: Saskia Aziza Nursyirwan, et al.
Published: (2017-12-01)

Predictors of parental acceptance to live attenuated influenza vaccine for children
by: Shujuan Qu, et al.
Published: (2024-12-01)

Predictors of yearly influenza vaccination in hospitalized and community based patients
by: Stephanie Attard Camilleri, et al.
Published: (2018-08-01)

Ibrutinib may impair serological responses to influenza vaccination
by: Abby P. Douglas, et al.
Published: (2017-10-01)

Cushing's disease management: glimpse into 2051
by: Dalan, Rinkoo, et al.
Published: (2022)

Association of systemic vitamin D on the course of dengue virus infection in adults: a single-centre dengue cohort study at a large institution in Singapore
by: Sapna P Sadarangani, et al.
Published: (2024-06-01)

Influenza and pneumococcal vaccination: do older people know if they have been vaccinated?
by: Alice Laurence, et al.
Published: (2016-06-01)

Reasons for nonadherence to vaccination for influenza among older people in Brazil.
by: Aldiane Gomes de Macedo Bacurau, et al.
Published: (2021-01-01)

Campaign, counseling and compliance with influenza vaccine among older persons
by: Vivian Iida Avelino-Silva, et al.
Published: (2011-01-01)

Reasons for nonadherence to vaccination for influenza among older people in Brazil
by: Aldiane Gomes de Macedo Bacurau, et al.
Published: (2021-01-01)

Cost-effectiveness of high-dose quadrivalent influenza vaccine versus standard-dose quadrivalent influenza vaccine for older people in a country with high influenza vaccination rate
by: Eliel Nham, et al.
Published: (2023-12-01)

Pandemic Influenza Vaccines: What did We Learn from the 2009 Pandemic and are We Better Prepared Now?
by: Steven Rockman, et al.
Published: (2020-05-01)

Glycated haemoglobin trajectories and one-year risk of potentially avoidable hospitalisations among adult patients with type 2 diabetes from specialist outpatient clinics of a tertiary hospital: a cohort study
by: Htun, Htet Lin, et al.
Published: (2023)

A comparison between the predictors of vaccine uptake intentions for influenza and dengue
by: Panchapakesan, Chitra, et al.
Published: (2025)

Acute exercise decreases vaccine reactions following influenza vaccination among older adults
by: Erika Bohn-Goldbaum, et al.
Published: (2020-01-01)

High-sensitivity C-reactive protein concentrations among patients with and without diabetes in a multiethnic population of Singapore: CREDENCE Study
by: Rinkoo Dalan, et al.
Published: (2010-06-01)

An Economic Evaluation of the Adjuvanted Quadrivalent Influenza Vaccine Compared with Standard-Dose Quadrivalent Influenza Vaccine in the Spanish Older Adult Population
by: Anna Fochesato, et al.
Published: (2022-08-01)

Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination
by: Lin Yang, et al.
Published: (2019-02-01)

Sociodemographic disparities in influenza vaccination among older adults in United States
by: Huan Tao, et al.
Published: (2025-02-01)

The memory B cell response to influenza vaccination is impaired in older persons
by: Alice R. Burton, et al.
Published: (2024-02-01)

Perspectives of Older Adults on COVID-19 and Influenza Vaccination in Ontario, Canada
by: Milena Music, et al.
Published: (2023-12-01)

Effectiveness of influenza vaccination on in-hospital death in older adults with respiratory diseases
by: Ruosu Zhang, et al.
Published: (2022-11-01)

Targeting the hallmarks of aging to improve influenza vaccine responses in older adults
by: Andreia N. Cadar, et al.
Published: (2023-05-01)

Correction: Reasons for nonadherence to vaccination for influenza among older people in Brazil.
by: Aldiane Gomes de Macedo Bacurau, et al.
Published: (2022-01-01)