Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV
Background/Aims Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the diffe...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Korean Association of Internal Medicine
2022-05-01
|
Series: | The Korean Journal of Internal Medicine |
Subjects: | |
Online Access: | http://www.kjim.org/upload/pdf/kjim-2021-539.pdf |
_version_ | 1818160635341438976 |
---|---|
author | Seok Oh Ju Han Kim Kyung Hoon Cho Min Chul Kim Doo Sun Sim Young Joon Hong Youngkeun Ahn Myung Ho Jeong |
author_facet | Seok Oh Ju Han Kim Kyung Hoon Cho Min Chul Kim Doo Sun Sim Young Joon Hong Youngkeun Ahn Myung Ho Jeong |
author_sort | Seok Oh |
collection | DOAJ |
description | Background/Aims Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the difference in long-term outcomes between off- and on-hour percutaneous coronary interventions (PCI) in patients with AMI of Killip functional classification III–IV (Killip III–IV AMI). Methods Data on the characteristics and clinical outcomes of 1,751 patients with Killip III–IV AMI between November 2011 and June 2015 from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were analyzed. All participants were allocated into two groups: off-hour (weekdays from 6:00 PM to 8:00 AM, weekends, and legal holidays) and on-hour (weekdays from 8:00 AM to 6:00 PM) groups. The incidence of major adverse cardiac and cerebrovascular events, defined as a composite of all-cause mortality, nonfatal myocardial infarction, any revascularization, cerebrovascular accident, and stent thrombosis, was the primary endpoint. Results Among the 1,751 patients, 572 (39.1%) underwent PCI during on-hours and 892 (60.9%) during off-hours. At the 3-year follow-up, no significant difference was found in the clinical outcomes between the two groups in both the unadjusted and propensity-score weighing-adjusted analyses. Conclusions The outcomes of patients with Killip III–IV AMI admitted during off- and on-hours were similar. |
first_indexed | 2024-12-11T16:05:01Z |
format | Article |
id | doaj.art-a1597ddef9d74ac79b930a50e6a39cf1 |
institution | Directory Open Access Journal |
issn | 1226-3303 2005-6648 |
language | English |
last_indexed | 2024-12-11T16:05:01Z |
publishDate | 2022-05-01 |
publisher | The Korean Association of Internal Medicine |
record_format | Article |
series | The Korean Journal of Internal Medicine |
spelling | doaj.art-a1597ddef9d74ac79b930a50e6a39cf12022-12-22T00:59:13ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482022-05-0137359160410.3904/kjim.2021.539170678Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IVSeok OhJu Han KimKyung Hoon ChoMin Chul KimDoo Sun SimYoung Joon HongYoungkeun AhnMyung Ho JeongBackground/Aims Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the difference in long-term outcomes between off- and on-hour percutaneous coronary interventions (PCI) in patients with AMI of Killip functional classification III–IV (Killip III–IV AMI). Methods Data on the characteristics and clinical outcomes of 1,751 patients with Killip III–IV AMI between November 2011 and June 2015 from the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were analyzed. All participants were allocated into two groups: off-hour (weekdays from 6:00 PM to 8:00 AM, weekends, and legal holidays) and on-hour (weekdays from 8:00 AM to 6:00 PM) groups. The incidence of major adverse cardiac and cerebrovascular events, defined as a composite of all-cause mortality, nonfatal myocardial infarction, any revascularization, cerebrovascular accident, and stent thrombosis, was the primary endpoint. Results Among the 1,751 patients, 572 (39.1%) underwent PCI during on-hours and 892 (60.9%) during off-hours. At the 3-year follow-up, no significant difference was found in the clinical outcomes between the two groups in both the unadjusted and propensity-score weighing-adjusted analyses. Conclusions The outcomes of patients with Killip III–IV AMI admitted during off- and on-hours were similar.http://www.kjim.org/upload/pdf/kjim-2021-539.pdfpercutaneous coronary interventionmyocardial infarctiontreatment outcomerepublic of koreaacute coronary syndrome |
spellingShingle | Seok Oh Ju Han Kim Kyung Hoon Cho Min Chul Kim Doo Sun Sim Young Joon Hong Youngkeun Ahn Myung Ho Jeong Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV The Korean Journal of Internal Medicine percutaneous coronary intervention myocardial infarction treatment outcome republic of korea acute coronary syndrome |
title | Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV |
title_full | Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV |
title_fullStr | Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV |
title_full_unstemmed | Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV |
title_short | Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV |
title_sort | off hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with killip iii iv |
topic | percutaneous coronary intervention myocardial infarction treatment outcome republic of korea acute coronary syndrome |
url | http://www.kjim.org/upload/pdf/kjim-2021-539.pdf |
work_keys_str_mv | AT seokoh offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT juhankim offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT kyunghooncho offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT minchulkim offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT doosunsim offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT youngjoonhong offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT youngkeunahn offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv AT myunghojeong offhourpresentationandoutcomesforpercutaneouscoronaryinterventioninacutemyocardialinfarctionwithkillipiiiiv |