STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION

In total, 43 patients with essential arterial hypertension (EAH) and 34 patients with isolated systolic arterial hypertension (ISAH) underwent echocardiography, Doppler echocardiography (Hewlet-Pacard Sonos 100, USA), and pulse wave velocity (PWV) assessment (Complier-2, France). All participants we...

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Main Authors: S. V. Gurgenyan, K. G. Adamyan, S. Kh. Vatinyan, K. G. Nikogosyan, P. A. Zelveyan
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2011-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1097
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author S. V. Gurgenyan
K. G. Adamyan
S. Kh. Vatinyan
K. G. Nikogosyan
P. A. Zelveyan
author_facet S. V. Gurgenyan
K. G. Adamyan
S. Kh. Vatinyan
K. G. Nikogosyan
P. A. Zelveyan
author_sort S. V. Gurgenyan
collection DOAJ
description In total, 43 patients with essential arterial hypertension (EAH) and 34 patients with isolated systolic arterial hypertension (ISAH) underwent echocardiography, Doppler echocardiography (Hewlet-Pacard Sonos 100, USA), and pulse wave velocity (PWV) assessment (Complier-2, France). All participants were divided into two groups: Group I – with concentric left ventricular hypertrophy (LVH): 27 (62,8%) EAH patients and 12 (35,3%) ISAH patients; and Group II – with eccentric LVH: 16 (37,2%) EAH patients and 22 (64,7%) ISAH patients. In EAH and ISAH, respectively, the most prevalent geometric LV models were concentric and eccentric LVH. Left atrium diameter and right ventricular (RV) outflow tract size were increased in all Group II patients. PWV was increased in both EAH and ISAH patients, to a greater extent among the latter. There was a positive correlation between systolic blood pressure, PWV and LVH parameters. In addition, there was a negative correlation between PWV and relative wall thickness (RWT). Diastolic LV function was impaired in all participants, while Group II patients demonstrated systolic LV dysfunction and diastolic RV dysfunction. LV myocardial mass index was inversely associated with E/A peak ratio. The study described the features of cardiovascular remodelling in EAH and ISAH. Typical structural and functional parameters of heart adaptation to increased workload were specified. The patients at high risk of congestive heart failure were identified.
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spelling doaj.art-a15bbc4b5dc04a22a2736ec3ab7db0f12023-03-29T21:23:17Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202011-04-01021720903STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSIONS. V. GurgenyanK. G. AdamyanS. Kh. VatinyanK. G. NikogosyanP. A. ZelveyanIn total, 43 patients with essential arterial hypertension (EAH) and 34 patients with isolated systolic arterial hypertension (ISAH) underwent echocardiography, Doppler echocardiography (Hewlet-Pacard Sonos 100, USA), and pulse wave velocity (PWV) assessment (Complier-2, France). All participants were divided into two groups: Group I – with concentric left ventricular hypertrophy (LVH): 27 (62,8%) EAH patients and 12 (35,3%) ISAH patients; and Group II – with eccentric LVH: 16 (37,2%) EAH patients and 22 (64,7%) ISAH patients. In EAH and ISAH, respectively, the most prevalent geometric LV models were concentric and eccentric LVH. Left atrium diameter and right ventricular (RV) outflow tract size were increased in all Group II patients. PWV was increased in both EAH and ISAH patients, to a greater extent among the latter. There was a positive correlation between systolic blood pressure, PWV and LVH parameters. In addition, there was a negative correlation between PWV and relative wall thickness (RWT). Diastolic LV function was impaired in all participants, while Group II patients demonstrated systolic LV dysfunction and diastolic RV dysfunction. LV myocardial mass index was inversely associated with E/A peak ratio. The study described the features of cardiovascular remodelling in EAH and ISAH. Typical structural and functional parameters of heart adaptation to increased workload were specified. The patients at high risk of congestive heart failure were identified.https://russjcardiol.elpub.ru/jour/article/view/1097essential arterial hypertensionisolated systolic arterial hypertensionconcentric hypertrophyeccentric hypertrophypulse wave velocitydiastolic functionsystolic function
spellingShingle S. V. Gurgenyan
K. G. Adamyan
S. Kh. Vatinyan
K. G. Nikogosyan
P. A. Zelveyan
STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
Российский кардиологический журнал
essential arterial hypertension
isolated systolic arterial hypertension
concentric hypertrophy
eccentric hypertrophy
pulse wave velocity
diastolic function
systolic function
title STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
title_full STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
title_fullStr STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
title_full_unstemmed STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
title_short STRUCTURAL AND FUNCTIONAL CARDIOVASCULAR REMODELLING IN ARTERIAL HYPERTENSION
title_sort structural and functional cardiovascular remodelling in arterial hypertension
topic essential arterial hypertension
isolated systolic arterial hypertension
concentric hypertrophy
eccentric hypertrophy
pulse wave velocity
diastolic function
systolic function
url https://russjcardiol.elpub.ru/jour/article/view/1097
work_keys_str_mv AT svgurgenyan structuralandfunctionalcardiovascularremodellinginarterialhypertension
AT kgadamyan structuralandfunctionalcardiovascularremodellinginarterialhypertension
AT skhvatinyan structuralandfunctionalcardiovascularremodellinginarterialhypertension
AT kgnikogosyan structuralandfunctionalcardiovascularremodellinginarterialhypertension
AT pazelveyan structuralandfunctionalcardiovascularremodellinginarterialhypertension