The JAK2 pathway is activated in idiopathic pulmonary fibrosis

The JAK2 pathway is activated in idiopathic pulmonary fibrosis

Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic disorder, with no curative therapies. The signal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts and alveolar type II cells (ATII), thereby contribu...

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Bibliographic Details
Main Authors: Javier Milara, Gracia Hernandez, Beatriz Ballester, Anselm Morell, Inés Roger, P. Montero, Juan Escrivá, José M. Lloris, Maria Molina-Molina, Esteban Morcillo, Julio Cortijo
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Respiratory Research
Subjects:
JAK2
STAT3
Idiopathic pulmonary fibrosis
Lung fibroblasts
Alveolar type II epithelial cells
Online Access:http://link.springer.com/article/10.1186/s12931-018-0728-9

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