Differential Pathogenic Th17 Profile in Mesenteric Lymph Nodes of Crohn's Disease and Ulcerative Colitis Patients

Differential Pathogenic Th17 Profile in Mesenteric Lymph Nodes of Crohn's Disease and Ulcerative Colitis Patients

The drug targets IL23 and IL12 regulate pathogenicity and plasticity of intestinal Th17 cells in Crohn's disease (CD) and ulcerative colitis (UC), the two most common inflammatory bowel diseases (IBD). However, studies examining Th17 dysregulation in mesenteric lymph nodes (mLNs) of these patie...

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Bibliographic Details
Main Authors: Marwa Bsat, Laurence Chapuy, Manuel Rubio, Ramses Wassef, Carole Richard, Frank Schwenter, Rasmy Loungnarath, Geneviève Soucy, Heena Mehta, Marika Sarfati
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
Th17 cells
mesenteric lymph nodes
inflammatory bowel disease
human
plasticity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01177/full

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