Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform
The rapid electrokinetic patterning (REP) technique has been demonstrated to enable dynamic particle manipulation in biomedical applications. Previous studies on REP have generally considered particles with a size less than 5 μm. In this study, a REP platform was used to manipulate polystyrene parti...
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MDPI AG
2022-12-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/13/12/2245 |
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| author | Sheng-Jie Zhang Zong-Rui Yang Ju-Nan Kuo |
| author_facet | Sheng-Jie Zhang Zong-Rui Yang Ju-Nan Kuo |
| author_sort | Sheng-Jie Zhang |
| collection | DOAJ |
| description | The rapid electrokinetic patterning (REP) technique has been demonstrated to enable dynamic particle manipulation in biomedical applications. Previous studies on REP have generally considered particles with a size less than 5 μm. In this study, a REP platform was used to manipulate polystyrene particles with a size of 3~11 μm in a microfluidic channel sandwiched between two ITO conductive glass plates. The effects of the synergy force produced by the REP electrothermal vortex on the particle motion were investigated numerically for fixed values of the laser power, AC driving voltage, and AC driving frequency, respectively. The simulation results showed that the particles were subject to a competition effect between the drag force produced by the toroidal vortex, which prompted the particles to recirculate in the bulk flow adjacent to the laser illumination spot on the lower electrode, and the trapping force produced by the particle and electrode interactions, which prompted the particles to aggregate in clusters on the surface of the illuminated spot. The experimental results showed that as the laser power increased, the toroidal flow range over which the particles circulated in the bulk flow increased, while the cluster range over which the particles were trapped on the electrode surface reduced. The results additionally showed that the particle velocity increased with an increasing laser power, particularly for particles with a smaller size. The excitation frequency at which the particles were trapped on the illuminated hot-spot reduced as the particle size increased. The force and velocity of polystyrene particles by the REP toroidal vortex has implications for further investigating the motion behavior at the biological cell level. |
| first_indexed | 2024-03-09T16:05:23Z |
| format | Article |
| id | doaj.art-a15f83c1e81f4a078473ea795274686b |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-09T16:05:23Z |
| publishDate | 2022-12-01 |
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| spelling | doaj.art-a15f83c1e81f4a078473ea795274686b2023-11-24T16:46:38ZengMDPI AGMicromachines2072-666X2022-12-011312224510.3390/mi13122245Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic PlatformSheng-Jie Zhang0Zong-Rui Yang1Ju-Nan Kuo2Department of Automation Engineering, National Formosa University, No. 64, Wenhua Rd., Huwei, Yunlin 632, TaiwanDepartment of Automation Engineering, National Formosa University, No. 64, Wenhua Rd., Huwei, Yunlin 632, TaiwanDepartment of Automation Engineering, National Formosa University, No. 64, Wenhua Rd., Huwei, Yunlin 632, TaiwanThe rapid electrokinetic patterning (REP) technique has been demonstrated to enable dynamic particle manipulation in biomedical applications. Previous studies on REP have generally considered particles with a size less than 5 μm. In this study, a REP platform was used to manipulate polystyrene particles with a size of 3~11 μm in a microfluidic channel sandwiched between two ITO conductive glass plates. The effects of the synergy force produced by the REP electrothermal vortex on the particle motion were investigated numerically for fixed values of the laser power, AC driving voltage, and AC driving frequency, respectively. The simulation results showed that the particles were subject to a competition effect between the drag force produced by the toroidal vortex, which prompted the particles to recirculate in the bulk flow adjacent to the laser illumination spot on the lower electrode, and the trapping force produced by the particle and electrode interactions, which prompted the particles to aggregate in clusters on the surface of the illuminated spot. The experimental results showed that as the laser power increased, the toroidal flow range over which the particles circulated in the bulk flow increased, while the cluster range over which the particles were trapped on the electrode surface reduced. The results additionally showed that the particle velocity increased with an increasing laser power, particularly for particles with a smaller size. The excitation frequency at which the particles were trapped on the illuminated hot-spot reduced as the particle size increased. The force and velocity of polystyrene particles by the REP toroidal vortex has implications for further investigating the motion behavior at the biological cell level.https://www.mdpi.com/2072-666X/13/12/2245velocity analysistoroidal vortexoptoelectrokineticREPdrag forcetrapping force |
| spellingShingle | Sheng-Jie Zhang Zong-Rui Yang Ju-Nan Kuo Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform Micromachines velocity analysis toroidal vortex optoelectrokinetic REP drag force trapping force |
| title | Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform |
| title_full | Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform |
| title_fullStr | Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform |
| title_full_unstemmed | Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform |
| title_short | Force and Velocity Analysis of Particles Manipulated by Toroidal Vortex on Optoelectrokinetic Microfluidic Platform |
| title_sort | force and velocity analysis of particles manipulated by toroidal vortex on optoelectrokinetic microfluidic platform |
| topic | velocity analysis toroidal vortex optoelectrokinetic REP drag force trapping force |
| url | https://www.mdpi.com/2072-666X/13/12/2245 |
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