New Application of the Commercially Available Dye Celestine Blue B as a Sensitive and Selective Fluorescent “Turn-On” Probe for Endogenous Detection of HOCl and Reactive Halogenated Species

New Application of the Commercially Available Dye Celestine Blue B as a Sensitive and Selective Fluorescent “Turn-On” Probe for Endogenous Detection of HOCl and Reactive Halogenated Species

Hypochlorous acid (HOCl) derived from hydrogen peroxide and chloride anion by myeloperoxidase (MPO) plays a significant role in physiological and pathological processes. Herein we report a phenoxazine-based fluorescent probe Celestine Blue B (CB) that is applicable for HOCl detection in living cells...

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Bibliographic Details
Main Authors: Veronika E. Reut, Stanislav O. Kozlov, Igor V. Kudryavtsev, Natalya A. Grudinina, Valeria A. Kostevich, Nikolay P. Gorbunov, Daria V. Grigorieva, Julia A. Kalvinkovskaya, Sergey B. Bushuk, Elena Yu Varfolomeeva, Natalia D. Fedorova, Irina V. Gorudko, Oleg M. Panasenko, Vadim B. Vasilyev, Alexey V. Sokolov
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
hypochlorous acid
myeloperoxidase
neutrophils
fluorescent probes
reactive halogen species
phenoxazine
Online Access:https://www.mdpi.com/2076-3921/11/9/1719

Internet

https://www.mdpi.com/2076-3921/11/9/1719

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