Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy
Background: psychiatric and behavioral side effects are common in patients with epilepsy and it may represent an intrinsic feature of the disease itself or a side effect of the antiepileptic use. Our aim in the present study is to assess the psychiatric side effects of Sodium Valproate and Carbamaz...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2008-12-01
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| Series: | مجله كليه طب الكندي |
| Subjects: | |
| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/747 |
| _version_ | 1828148300662964224 |
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| author | Zeki Noah Hasan Abdul- Rasul Al Yasiri Hassan Aziz Hassan |
| author_facet | Zeki Noah Hasan Abdul- Rasul Al Yasiri Hassan Aziz Hassan |
| author_sort | Zeki Noah Hasan |
| collection | DOAJ |
| description |
Background: psychiatric and behavioral side effects
are common in patients with epilepsy and it may
represent an intrinsic feature of the disease itself or a
side effect of the antiepileptic use. Our aim in the
present study is to assess the psychiatric side effects of
Sodium Valproate and Carbamazipine .as these drugs
are the most commonly used antiepileptic drugs in Iraq.
Methods: 80 patients with primary generalized
epilepsy on Carbamazipine and 50 patients on Sodium
Valproate were enrolled in the present study; all the
patients were assessed for any psychological
disturbances using semi-structural interview based on
the tenth edition of the international classification of
the diseases(ICD 10) adopted by WHO.
Results: Thirty percent of patients taking Sodium
Valproate and (9%) of patients taking Carbamazipine
were found to have depression while (16%) of patients
taking Sodium Valproate and (20 %) of patients taking
Carbamazipine were found to have anxiety. There were
no reported psychosis, suicidal attempts, cognitive
deficit and mania in both groups of patients in the
present study.
Conclusion: Carbamazipine is preferred to Sodium
Valproate when the efficacy of both drugs is
comparable.
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| first_indexed | 2024-04-11T21:14:00Z |
| format | Article |
| id | doaj.art-a1660fbaea62456094366290173e43aa |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T21:14:00Z |
| publishDate | 2008-12-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-a1660fbaea62456094366290173e43aa2022-12-22T04:02:53ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652008-12-0142Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized EpilepsyZeki Noah Hasan0Abdul- Rasul Al Yasiri1Hassan Aziz Hassan2Head of Neurology .Department. Al-kindyCollage of Medicine** Head of Psychiatry .Department. Al-kindi Collage of MedicineHead of Neurology .Department. Al-Nahrin Collage of Medicine. Background: psychiatric and behavioral side effects are common in patients with epilepsy and it may represent an intrinsic feature of the disease itself or a side effect of the antiepileptic use. Our aim in the present study is to assess the psychiatric side effects of Sodium Valproate and Carbamazipine .as these drugs are the most commonly used antiepileptic drugs in Iraq. Methods: 80 patients with primary generalized epilepsy on Carbamazipine and 50 patients on Sodium Valproate were enrolled in the present study; all the patients were assessed for any psychological disturbances using semi-structural interview based on the tenth edition of the international classification of the diseases(ICD 10) adopted by WHO. Results: Thirty percent of patients taking Sodium Valproate and (9%) of patients taking Carbamazipine were found to have depression while (16%) of patients taking Sodium Valproate and (20 %) of patients taking Carbamazipine were found to have anxiety. There were no reported psychosis, suicidal attempts, cognitive deficit and mania in both groups of patients in the present study. Conclusion: Carbamazipine is preferred to Sodium Valproate when the efficacy of both drugs is comparable. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/747antiepileptic drugsSodium valproateCarbamazipinedepressionanxietypsychiatric side effects |
| spellingShingle | Zeki Noah Hasan Abdul- Rasul Al Yasiri Hassan Aziz Hassan Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy مجله كليه طب الكندي antiepileptic drugs Sodium valproate Carbamazipine depression anxiety psychiatric side effects |
| title | Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy |
| title_full | Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy |
| title_fullStr | Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy |
| title_full_unstemmed | Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy |
| title_short | Psychiatric Squele of Sodium Valproate Versus Carbamazipine In Patients with Primary Generalized Epilepsy |
| title_sort | psychiatric squele of sodium valproate versus carbamazipine in patients with primary generalized epilepsy |
| topic | antiepileptic drugs Sodium valproate Carbamazipine depression anxiety psychiatric side effects |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/747 |
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