A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study
In patients presenting mucositis, effective sub-gingival debridement is crucial to prevent peri-implantitis. The aim of this randomized study was to assess the three-month (T1) effects of a locally delivered liquid desiccant agent with molecular hygroscopic properties, in association with manual deb...
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MDPI AG
2019-06-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/8/2/82 |
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| author | Giorgio Lombardo Annarita Signoriello Giovanni Corrocher Caterina Signoretto Gloria Burlacchini Alessia Pardo Pier Francesco Nocini |
| author_facet | Giorgio Lombardo Annarita Signoriello Giovanni Corrocher Caterina Signoretto Gloria Burlacchini Alessia Pardo Pier Francesco Nocini |
| author_sort | Giorgio Lombardo |
| collection | DOAJ |
| description | In patients presenting mucositis, effective sub-gingival debridement is crucial to prevent peri-implantitis. The aim of this randomized study was to assess the three-month (T1) effects of a locally delivered liquid desiccant agent with molecular hygroscopic properties, in association with manual debridement, at sites with peri-implant mucositis. Twenty-three patients presenting at least one implant with no radiographically detectable bone loss, a pocket probing depth (PPD) ≥ 4 mm, and bleeding on probing (BOP), were included. At baseline (T0), patients were randomly assigned to receive the aforementioned desiccant agent before debridement (Test-Group), or a Chlorhexidine 1% disinfectant gel after debridement (Control-Group). Treatments were repeated after seven and 14 days. Peri-implant soft tissue assessment [PPD, BOP, Modified Bleeding Index (mBI), Visible Plaque Index (VPI), and Modified Plaque Index (mPLI)] and microbial sampling were performed at T0 and T1. At T1 the Test-Group presented significantly greater reductions for BOP, mBI, VPI, and mPLI. Concerning the deepest sites of the treated implants, both groups showed statistically significant reductions for BOP and mBI between T0 and T1. Furthermore, the Test-Group exhibited a significant decrease in anaerobic bacteria. Despite these valid outcomes, a complete resolution of the inflammatory conditions was not achieved by any of the groups. |
| first_indexed | 2024-12-20T20:07:51Z |
| format | Article |
| id | doaj.art-a166b900d7224e22b0581ec4926a0fbb |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-12-20T20:07:51Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-a166b900d7224e22b0581ec4926a0fbb2022-12-21T19:27:54ZengMDPI AGAntibiotics2079-63822019-06-01828210.3390/antibiotics8020082antibiotics8020082A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot StudyGiorgio Lombardo0Annarita Signoriello1Giovanni Corrocher2Caterina Signoretto3Gloria Burlacchini4Alessia Pardo5Pier Francesco Nocini6Dentistry and Maxillo-facial Surgery Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyDentistry and Maxillo-facial Surgery Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyDentistry and Maxillo-facial Surgery Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyMicrobiology Section, Department of Diagnostics and Public Health, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyMicrobiology Section, Department of Diagnostics and Public Health, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyDentistry and Maxillo-facial Surgery Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyDentistry and Maxillo-facial Surgery Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, ItalyIn patients presenting mucositis, effective sub-gingival debridement is crucial to prevent peri-implantitis. The aim of this randomized study was to assess the three-month (T1) effects of a locally delivered liquid desiccant agent with molecular hygroscopic properties, in association with manual debridement, at sites with peri-implant mucositis. Twenty-three patients presenting at least one implant with no radiographically detectable bone loss, a pocket probing depth (PPD) ≥ 4 mm, and bleeding on probing (BOP), were included. At baseline (T0), patients were randomly assigned to receive the aforementioned desiccant agent before debridement (Test-Group), or a Chlorhexidine 1% disinfectant gel after debridement (Control-Group). Treatments were repeated after seven and 14 days. Peri-implant soft tissue assessment [PPD, BOP, Modified Bleeding Index (mBI), Visible Plaque Index (VPI), and Modified Plaque Index (mPLI)] and microbial sampling were performed at T0 and T1. At T1 the Test-Group presented significantly greater reductions for BOP, mBI, VPI, and mPLI. Concerning the deepest sites of the treated implants, both groups showed statistically significant reductions for BOP and mBI between T0 and T1. Furthermore, the Test-Group exhibited a significant decrease in anaerobic bacteria. Despite these valid outcomes, a complete resolution of the inflammatory conditions was not achieved by any of the groups.https://www.mdpi.com/2079-6382/8/2/82peri-implant mucositismanual debridementdesiccant agentdisinfectant gelsoft tissuesmicrobial sampling |
| spellingShingle | Giorgio Lombardo Annarita Signoriello Giovanni Corrocher Caterina Signoretto Gloria Burlacchini Alessia Pardo Pier Francesco Nocini A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study Antibiotics peri-implant mucositis manual debridement desiccant agent disinfectant gel soft tissues microbial sampling |
| title | A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study |
| title_full | A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study |
| title_fullStr | A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study |
| title_full_unstemmed | A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study |
| title_short | A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study |
| title_sort | topical desiccant agent in association with manual debridement in the initial treatment of peri implant mucositis a clinical and microbiological pilot study |
| topic | peri-implant mucositis manual debridement desiccant agent disinfectant gel soft tissues microbial sampling |
| url | https://www.mdpi.com/2079-6382/8/2/82 |
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