Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies

Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies

The enzyme reverse transcriptase (RT) plays a central role in the life cycle of human immunodeficiency virus (HIV), and RT has been an important drug target. Elucidations of the RT structures trapping and detailing the enzyme at various functional and conformational states by X-ray crystallography h...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Abhimanyu K. Singh, Kalyan Das
Ձևաչափ:	Հոդված
Լեզու:	English
Հրապարակվել է:	MDPI AG 2022-05-01
Շարք:	Viruses
Խորագրեր:	HIV-RT NRTI NNRTI drug design structural biology crystallography
Առցանց հասանելիություն:	https://www.mdpi.com/1999-4915/14/5/1027

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