Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies

The enzyme reverse transcriptase (RT) plays a central role in the life cycle of human immunodeficiency virus (HIV), and RT has been an important drug target. Elucidations of the RT structures trapping and detailing the enzyme at various functional and conformational states by X-ray crystallography h...

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Manylion Llyfryddiaeth
Prif Awduron: Abhimanyu K. Singh, Kalyan Das
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2022-05-01
Cyfres:Viruses
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/1999-4915/14/5/1027