MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells

MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells

Abstract Background Protein-tyrosine phosphatase MEG2 (MEG2) is a classic tyrosine-specific protein tyrosine phosphatase (PTP). It has been reported that MEG2 participates in the carcinogenesis of the breast and liver. However, functions of MEG2 in gastric cancer remain poorly understood. Methods We...

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Bibliographic Details
Main Authors: Zhijian Liu, Feng Sun, Yeting Hong, Yanqing Liu, Min Fen, Kai Yin, Xiaolong Ge, Feng Wang, Xi Chen, Wenxian Guan
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Molecular Cancer
Subjects:
Gastric cancer
Protein-tyrosine phosphatase MEG2
miR-181a-5p
microRNA
Online Access:http://link.springer.com/article/10.1186/s12943-017-0695-7

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