The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making
Previous studies have demonstrated that the rate of evidence integration during perceptual decision making, a specific computationally defined parameter, is negatively correlated with both subclinical symptoms of OCD measured on a continuum and categorically diagnosed patient status. However, the ne...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | NeuroImage: Clinical |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158222000407 |
| _version_ | 1811233807638986752 |
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| author | Alec Solway Isabella Schneider Yuqing Lei |
| author_facet | Alec Solway Isabella Schneider Yuqing Lei |
| author_sort | Alec Solway |
| collection | DOAJ |
| description | Previous studies have demonstrated that the rate of evidence integration during perceptual decision making, a specific computationally defined parameter, is negatively correlated with both subclinical symptoms of OCD measured on a continuum and categorically diagnosed patient status. However, the neural mechanisms underlying this deficit are unknown. Separate work has shown that both gamma and beta-band power are related to evidence integration, and differences in beta-band power in particular have been hypothesized to hinder flexible behavioral control. We sought to unify these two disparate literatures, one on OCD-related information processing differences constrained by behavioral data alone, and the other on the neural correlates of evidence integration. Using computational modeling and scalp EEG, we tested (N = 67) the relationships between subclinical symptom scores, drift rate, and gamma/beta-band activity during perceptual decision making. We replicated both prior work showing deficits in evidence integration as a function of OCD symptoms, and work showing a relationship between evidence integration and gamma and beta-band power. As predicted, the slope of beta-band power was correlated with OCD symptoms. However, the relationships between OCD symptoms and drift rate and the slopes of gamma and beta-band power and drift rate remained unchanged when simultaneously accounting for all variables, speaking against the hypothesis that differences in band-band power explain drift rate deficits. |
| first_indexed | 2024-04-12T11:25:43Z |
| format | Article |
| id | doaj.art-a17296a78f1840f1be0999312584d38f |
| institution | Directory Open Access Journal |
| issn | 2213-1582 |
| language | English |
| last_indexed | 2024-04-12T11:25:43Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage: Clinical |
| spelling | doaj.art-a17296a78f1840f1be0999312584d38f2022-12-22T03:35:14ZengElsevierNeuroImage: Clinical2213-15822022-01-0134102975The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision makingAlec Solway0Isabella Schneider1Yuqing Lei2Department of Psychology, University of Maryland-College Park, United States; Program in Neuroscience and Cognitive Science, University of Maryland-College Park, United States; Corresponding author at: Department of Psychology, 4094 Campus Dr., College Park, MD 20742, United States.Department of Psychology, University of Maryland-College Park, United StatesDepartment of Psychology, University of Maryland-College Park, United StatesPrevious studies have demonstrated that the rate of evidence integration during perceptual decision making, a specific computationally defined parameter, is negatively correlated with both subclinical symptoms of OCD measured on a continuum and categorically diagnosed patient status. However, the neural mechanisms underlying this deficit are unknown. Separate work has shown that both gamma and beta-band power are related to evidence integration, and differences in beta-band power in particular have been hypothesized to hinder flexible behavioral control. We sought to unify these two disparate literatures, one on OCD-related information processing differences constrained by behavioral data alone, and the other on the neural correlates of evidence integration. Using computational modeling and scalp EEG, we tested (N = 67) the relationships between subclinical symptom scores, drift rate, and gamma/beta-band activity during perceptual decision making. We replicated both prior work showing deficits in evidence integration as a function of OCD symptoms, and work showing a relationship between evidence integration and gamma and beta-band power. As predicted, the slope of beta-band power was correlated with OCD symptoms. However, the relationships between OCD symptoms and drift rate and the slopes of gamma and beta-band power and drift rate remained unchanged when simultaneously accounting for all variables, speaking against the hypothesis that differences in band-band power explain drift rate deficits.http://www.sciencedirect.com/science/article/pii/S2213158222000407BetaGammaDecision makingObsessive-compulsive disorderComputational modelingDrift-diffusion model |
| spellingShingle | Alec Solway Isabella Schneider Yuqing Lei The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making NeuroImage: Clinical Beta Gamma Decision making Obsessive-compulsive disorder Computational modeling Drift-diffusion model |
| title | The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making |
| title_full | The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making |
| title_fullStr | The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making |
| title_full_unstemmed | The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making |
| title_short | The relationships between subclinical OCD symptoms, beta/gamma-band power, and the rate of evidence integration during perceptual decision making |
| title_sort | relationships between subclinical ocd symptoms beta gamma band power and the rate of evidence integration during perceptual decision making |
| topic | Beta Gamma Decision making Obsessive-compulsive disorder Computational modeling Drift-diffusion model |
| url | http://www.sciencedirect.com/science/article/pii/S2213158222000407 |
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