Asymptomatic shedding of herpes simplex virus in oral cavity
Herpes simplex virus (HSV) is a significant human pathogen. Dental surgeons and Dental Hygienists come across many patients which are not having clinical symptoms but are the carriers of the disease. The person working in the oral cavity is at high risk for getting infected and also the risk of cros...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Indian Academy of Oral Medicine and Radiology |
| Subjects: | |
| Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2021;volume=33;issue=1;spage=22;epage=26;aulast=Kulkarni |
| _version_ | 1818948005528600576 |
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| author | Abhay Kulkarni Shruti Wadne Rajendra Birangane Rohan Chaudhari Nitin Kole Supriya Sankpal |
| author_facet | Abhay Kulkarni Shruti Wadne Rajendra Birangane Rohan Chaudhari Nitin Kole Supriya Sankpal |
| author_sort | Abhay Kulkarni |
| collection | DOAJ |
| description | Herpes simplex virus (HSV) is a significant human pathogen. Dental surgeons and Dental Hygienists come across many patients which are not having clinical symptoms but are the carriers of the disease. The person working in the oral cavity is at high risk for getting infected and also the risk of cross-infection in the general population. Aim: In this study, we determine the prevalence of HSV qualitatively and quantitatively in the oral cavity in apparently asymptomatic patients. Study Setting: Institutional and PCR testing Labs. Methods & Materials: The study analyzed saliva samples derived from 220 individuals which were collected with sterile swabs. The traditional PCR method was done for qualitative analysis and real-time PCR for the quantitative analysis. Results: The results of qualitative analysis showed that HSV-2 was more commonly shed than HSV-1 in the oral cavity, while the infected persons showed more genomic copy numbers. Conclusion: The presence of asymptomatic shedding of HSV-2 may be an indicator of future immunosuppression which should be followed up. |
| first_indexed | 2024-12-20T08:39:55Z |
| format | Article |
| id | doaj.art-a174b0911bc14d22bd509cb123dbe41c |
| institution | Directory Open Access Journal |
| issn | 0972-1363 |
| language | English |
| last_indexed | 2024-12-20T08:39:55Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Academy of Oral Medicine and Radiology |
| spelling | doaj.art-a174b0911bc14d22bd509cb123dbe41c2022-12-21T19:46:26ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632021-01-01331222610.4103/jiaomr.jiaomr_231_20Asymptomatic shedding of herpes simplex virus in oral cavityAbhay KulkarniShruti WadneRajendra BiranganeRohan ChaudhariNitin KoleSupriya SankpalHerpes simplex virus (HSV) is a significant human pathogen. Dental surgeons and Dental Hygienists come across many patients which are not having clinical symptoms but are the carriers of the disease. The person working in the oral cavity is at high risk for getting infected and also the risk of cross-infection in the general population. Aim: In this study, we determine the prevalence of HSV qualitatively and quantitatively in the oral cavity in apparently asymptomatic patients. Study Setting: Institutional and PCR testing Labs. Methods & Materials: The study analyzed saliva samples derived from 220 individuals which were collected with sterile swabs. The traditional PCR method was done for qualitative analysis and real-time PCR for the quantitative analysis. Results: The results of qualitative analysis showed that HSV-2 was more commonly shed than HSV-1 in the oral cavity, while the infected persons showed more genomic copy numbers. Conclusion: The presence of asymptomatic shedding of HSV-2 may be an indicator of future immunosuppression which should be followed up.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2021;volume=33;issue=1;spage=22;epage=26;aulast=Kulkarniherpes simplex virussubclinical reactivationviral genome copy number |
| spellingShingle | Abhay Kulkarni Shruti Wadne Rajendra Birangane Rohan Chaudhari Nitin Kole Supriya Sankpal Asymptomatic shedding of herpes simplex virus in oral cavity Journal of Indian Academy of Oral Medicine and Radiology herpes simplex virus subclinical reactivation viral genome copy number |
| title | Asymptomatic shedding of herpes simplex virus in oral cavity |
| title_full | Asymptomatic shedding of herpes simplex virus in oral cavity |
| title_fullStr | Asymptomatic shedding of herpes simplex virus in oral cavity |
| title_full_unstemmed | Asymptomatic shedding of herpes simplex virus in oral cavity |
| title_short | Asymptomatic shedding of herpes simplex virus in oral cavity |
| title_sort | asymptomatic shedding of herpes simplex virus in oral cavity |
| topic | herpes simplex virus subclinical reactivation viral genome copy number |
| url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2021;volume=33;issue=1;spage=22;epage=26;aulast=Kulkarni |
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