Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children

<p>Abstract</p> <p>Objective</p> <p>The main objective of this study was to assess the quality of home malaria management with pre-packaged chloroquine in two areas in the Moramanga district of Madagascar. The knowledge, attitude and practices of care providers in terms...

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Main Authors: Malvy Denis, Rakotoson Benjamin, Rabarijaona Leon, Soarès Jean, Millet Pascal, Randrianarivelojosia Milijaona, Ratsimbasoa Arsène, Ménard Didier
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/5/1/79
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author Malvy Denis
Rakotoson Benjamin
Rabarijaona Leon
Soarès Jean
Millet Pascal
Randrianarivelojosia Milijaona
Ratsimbasoa Arsène
Ménard Didier
author_facet Malvy Denis
Rakotoson Benjamin
Rabarijaona Leon
Soarès Jean
Millet Pascal
Randrianarivelojosia Milijaona
Ratsimbasoa Arsène
Ménard Didier
author_sort Malvy Denis
collection DOAJ
description <p>Abstract</p> <p>Objective</p> <p>The main objective of this study was to assess the quality of home malaria management with pre-packaged chloroquine in two areas in the Moramanga district of Madagascar. The knowledge, attitude and practices of care providers in terms of home treatment options were evaluated and compared. The availability of treatment options by studying retailers and community-based service providers was also investigated.</p> <p>Methods</p> <p>A cross-sectional investigation in two communities, in the hamlets and villages located close to carers, retailers, community-based service providers and primary health centres was carried out.</p> <p>Results</p> <p>Carers in the two districts were equally well aware of the use of pre-packaged chloroquine. Their first response to the onset of fever was to treat children with this antimalarial drug at home. The dose administered and treatment compliance were entirely satisfactory (100%) with pre-packaged chloroquine and rarely satisfactory (1.6% to 4.5%) with non pre-packaged chloroquine. In cases of treatment failure, the carers took patients to health centres. Chloroquine was supplied principally by private pharmacies and travelling salesmen selling unpackaged chloroquine tablets. Non pre-packaged chloroquine was the most common drug used at health centres. The frequency of positive rapid malaria tests (P = 0.01) was significantly higher in children treated with non pre-packaged chloroquine (38%) than in children treated with pre-packaged chloroquine (1.3%).</p> <p>Conclusion</p> <p>Home malaria management should be improved in Madagascar. Efforts should focus on communication, the training of community-based service providers, access to pre-packaged drugs and the gradual withdrawal of pre-packaged chloroquine and its replacement by pre-packaged artemisinin-based combination therapies.</p>
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spelling doaj.art-a1756be128e944899bc175fc1b33132b2022-12-22T03:17:10ZengBMCMalaria Journal1475-28752006-09-01517910.1186/1475-2875-5-79Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy childrenMalvy DenisRakotoson BenjaminRabarijaona LeonSoarès JeanMillet PascalRandrianarivelojosia MilijaonaRatsimbasoa ArsèneMénard Didier<p>Abstract</p> <p>Objective</p> <p>The main objective of this study was to assess the quality of home malaria management with pre-packaged chloroquine in two areas in the Moramanga district of Madagascar. The knowledge, attitude and practices of care providers in terms of home treatment options were evaluated and compared. The availability of treatment options by studying retailers and community-based service providers was also investigated.</p> <p>Methods</p> <p>A cross-sectional investigation in two communities, in the hamlets and villages located close to carers, retailers, community-based service providers and primary health centres was carried out.</p> <p>Results</p> <p>Carers in the two districts were equally well aware of the use of pre-packaged chloroquine. Their first response to the onset of fever was to treat children with this antimalarial drug at home. The dose administered and treatment compliance were entirely satisfactory (100%) with pre-packaged chloroquine and rarely satisfactory (1.6% to 4.5%) with non pre-packaged chloroquine. In cases of treatment failure, the carers took patients to health centres. Chloroquine was supplied principally by private pharmacies and travelling salesmen selling unpackaged chloroquine tablets. Non pre-packaged chloroquine was the most common drug used at health centres. The frequency of positive rapid malaria tests (P = 0.01) was significantly higher in children treated with non pre-packaged chloroquine (38%) than in children treated with pre-packaged chloroquine (1.3%).</p> <p>Conclusion</p> <p>Home malaria management should be improved in Madagascar. Efforts should focus on communication, the training of community-based service providers, access to pre-packaged drugs and the gradual withdrawal of pre-packaged chloroquine and its replacement by pre-packaged artemisinin-based combination therapies.</p>http://www.malariajournal.com/content/5/1/79
spellingShingle Malvy Denis
Rakotoson Benjamin
Rabarijaona Leon
Soarès Jean
Millet Pascal
Randrianarivelojosia Milijaona
Ratsimbasoa Arsène
Ménard Didier
Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
Malaria Journal
title Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
title_full Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
title_fullStr Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
title_full_unstemmed Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
title_short Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children
title_sort use of pre packaged chloroquine for the home management of presumed malaria in malagasy children
url http://www.malariajournal.com/content/5/1/79
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