Infantile Hemangiomas: An Update on Pathogenesis and Treatment
Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different treatment methods. Although most infantile hemangio...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/20/4631 |
| _version_ | 1797514256401301504 |
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| author | Małgorzata Kowalska Wojciech Dębek Ewa Matuszczak |
| author_facet | Małgorzata Kowalska Wojciech Dębek Ewa Matuszczak |
| author_sort | Małgorzata Kowalska |
| collection | DOAJ |
| description | Infantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different treatment methods. Although most infantile hemangiomas require only active observation because of their natural course, which results in involution, about 10% present with complications that require immediate treatment. The basic treatment includes systemic and topical options. In cases of insufficient response or rebound growth, other forms of treatment should be considered. In some cases, combined therapy might be initiated. |
| first_indexed | 2024-03-10T06:29:03Z |
| format | Article |
| id | doaj.art-a17899fa04e249989745af7aaf5190c0 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:29:03Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a17899fa04e249989745af7aaf5190c02023-11-22T18:40:37ZengMDPI AGJournal of Clinical Medicine2077-03832021-10-011020463110.3390/jcm10204631Infantile Hemangiomas: An Update on Pathogenesis and TreatmentMałgorzata Kowalska0Wojciech Dębek1Ewa Matuszczak2Department of Pediatric Surgery and Pediatric Urology, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, PolandDepartment of Pediatric Surgery and Pediatric Urology, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, PolandDepartment of Pediatric Surgery and Pediatric Urology, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, PolandInfantile hemangiomas are the most common benign vascular tumors in infancy. This review includes an update on the current knowledge on pathogenesis, a discussion on indications for treatment, and a review of the mechanisms underlying the different treatment methods. Although most infantile hemangiomas require only active observation because of their natural course, which results in involution, about 10% present with complications that require immediate treatment. The basic treatment includes systemic and topical options. In cases of insufficient response or rebound growth, other forms of treatment should be considered. In some cases, combined therapy might be initiated.https://www.mdpi.com/2077-0383/10/20/4631infantile hemangiomapropranololPDL |
| spellingShingle | Małgorzata Kowalska Wojciech Dębek Ewa Matuszczak Infantile Hemangiomas: An Update on Pathogenesis and Treatment Journal of Clinical Medicine infantile hemangioma propranolol PDL |
| title | Infantile Hemangiomas: An Update on Pathogenesis and Treatment |
| title_full | Infantile Hemangiomas: An Update on Pathogenesis and Treatment |
| title_fullStr | Infantile Hemangiomas: An Update on Pathogenesis and Treatment |
| title_full_unstemmed | Infantile Hemangiomas: An Update on Pathogenesis and Treatment |
| title_short | Infantile Hemangiomas: An Update on Pathogenesis and Treatment |
| title_sort | infantile hemangiomas an update on pathogenesis and treatment |
| topic | infantile hemangioma propranolol PDL |
| url | https://www.mdpi.com/2077-0383/10/20/4631 |
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