Billiary secretion of rats liver upon hydrocortizone load
It was investigated the influence of hydrocortisone (40 mg/kg b wt) on bile secretion of acute experiment on rats. It was estimated that this hormone promoted increasing of bile acids conjugation with taurin and glycine in rat hepatocytes and provided a minor choleretic effect. It should be indicate...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taras Shevchenko National University of Kyiv
2016-11-01
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| Series: | Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
| Subjects: | |
| Online Access: | http://biovestnik.com/index.php/biology/article/view/126 |
| _version_ | 1797716405727002624 |
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| author | Yu. Vinnyk P. Tsapenko T. Lyaschenko S. Veselsky |
| author_facet | Yu. Vinnyk P. Tsapenko T. Lyaschenko S. Veselsky |
| author_sort | Yu. Vinnyk |
| collection | DOAJ |
| description | It was investigated the influence of hydrocortisone (40 mg/kg b wt) on bile secretion of acute experiment on rats. It was estimated that this hormone promoted increasing of bile acids conjugation with taurin and glycine in rat hepatocytes and provided a minor choleretic effect. It should be indicated that loading of mentioned dose improve solubilisating and colloidal properties of the bile. It was observed significant decrease of freebile-acid level under conditions of hydrocortisone-induced stress. It may be partially caused by inhibition effect of hormone on enzymatic system. |
| first_indexed | 2024-03-12T08:20:57Z |
| format | Article |
| id | doaj.art-a1793e1b2010410c9cac71923314e9bc |
| institution | Directory Open Access Journal |
| issn | 1728-2748 2308-8036 |
| language | English |
| last_indexed | 2024-03-12T08:20:57Z |
| publishDate | 2016-11-01 |
| publisher | Taras Shevchenko National University of Kyiv |
| record_format | Article |
| series | Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
| spelling | doaj.art-a1793e1b2010410c9cac71923314e9bc2023-09-02T18:29:49ZengTaras Shevchenko National University of KyivVìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ1728-27482308-80362016-11-016615155117Billiary secretion of rats liver upon hydrocortizone loadYu. Vinnyk0P. Tsapenko1T. Lyaschenko2S. Veselsky3Taras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivIt was investigated the influence of hydrocortisone (40 mg/kg b wt) on bile secretion of acute experiment on rats. It was estimated that this hormone promoted increasing of bile acids conjugation with taurin and glycine in rat hepatocytes and provided a minor choleretic effect. It should be indicated that loading of mentioned dose improve solubilisating and colloidal properties of the bile. It was observed significant decrease of freebile-acid level under conditions of hydrocortisone-induced stress. It may be partially caused by inhibition effect of hormone on enzymatic system.http://biovestnik.com/index.php/biology/article/view/126hydrocortisone, bile acids |
| spellingShingle | Yu. Vinnyk P. Tsapenko T. Lyaschenko S. Veselsky Billiary secretion of rats liver upon hydrocortizone load Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ hydrocortisone, bile acids |
| title | Billiary secretion of rats liver upon hydrocortizone load |
| title_full | Billiary secretion of rats liver upon hydrocortizone load |
| title_fullStr | Billiary secretion of rats liver upon hydrocortizone load |
| title_full_unstemmed | Billiary secretion of rats liver upon hydrocortizone load |
| title_short | Billiary secretion of rats liver upon hydrocortizone load |
| title_sort | billiary secretion of rats liver upon hydrocortizone load |
| topic | hydrocortisone, bile acids |
| url | http://biovestnik.com/index.php/biology/article/view/126 |
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