Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits
Objective Angora rabbits fed a low-protein diet exhibit decreased hair production performance. This study was set out to evaluate the effects of methionine on hair properties and nitrogen metabolism in Angora rabbits fed a low-protein diet and to investigate the gene expression related to hair folli...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Asian-Australasian Association of Animal Production Societies
2023-06-01
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| Series: | Animal Bioscience |
| Subjects: | |
| Online Access: | http://www.animbiosci.org/upload/pdf/ab-22-0286.pdf |
| _version_ | 1797831766576201728 |
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| author | Man Zhao Tongtong Wang Bin Wang Chuanhua Liu Fuchang Li Lei Liu |
| author_facet | Man Zhao Tongtong Wang Bin Wang Chuanhua Liu Fuchang Li Lei Liu |
| author_sort | Man Zhao |
| collection | DOAJ |
| description | Objective Angora rabbits fed a low-protein diet exhibit decreased hair production performance. This study was set out to evaluate the effects of methionine on hair properties and nitrogen metabolism in Angora rabbits fed a low-protein diet and to investigate the gene expression related to hair follicle development to determine the possible molecular mechanism of methionine effects on hair follicle development. Methods An experiment was conducted to investigate the effects of DL-methionine addition on a low-protein diet on hair development in Angora rabbits. Angora rabbits were divided into 5 groups: fed a normal diet (control), fed a low-protein diet (LP), or fed an LP supplemented with 0.2%, 0.4%, or 0.6% DL-methionine (Met). Results The results showed that rabbits in the LP group had lower wool yield than the control rabbits, but the addition of 0.4% to 0.6% Met to LP attenuated these effects (p< 0.05). Dietary addition of 0.4% to 0.6% Met to LP increased the apparent nitrogen digestibility, nitrogen utilization rate, and feed efficiency (p<0.05). Feeding LP decreased the insulin-like growth factor 1 (IGF1), keratin-associated protein (KAP) 3.1, and KAP 6.1 mRNA levels compared with the control, but the addition of 0.4% Met in LP attenuated these effects (p<0.05). Relative to the LP or control group, dietary addition of 0.4% Met increased versican mRNA levels. Conclusion In conclusion, the addition of Met to LP could improves wool production performance and feed efficiency and reduce nitrogen emissions in Angora rabbits. Met can promote hair follicle development, which may be associated with IGF1, KAP, and the versican signaling. |
| first_indexed | 2024-04-09T13:58:03Z |
| format | Article |
| id | doaj.art-a179553a2ccb44d2b2d72a4e734c758b |
| institution | Directory Open Access Journal |
| issn | 2765-0189 2765-0235 |
| language | English |
| last_indexed | 2024-04-09T13:58:03Z |
| publishDate | 2023-06-01 |
| publisher | Asian-Australasian Association of Animal Production Societies |
| record_format | Article |
| series | Animal Bioscience |
| spelling | doaj.art-a179553a2ccb44d2b2d72a4e734c758b2023-05-07T23:25:09ZengAsian-Australasian Association of Animal Production SocietiesAnimal Bioscience2765-01892765-02352023-06-0136692092810.5713/ab.22.028624982Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbitsMan Zhao0Tongtong Wang1Bin Wang2Chuanhua Liu3Fuchang Li4Lei Liu5 Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Department of Animal Science, Shandong Agricultural University, Taian, Shandong 271018, China Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Department of Animal Science, Shandong Agricultural University, Taian, Shandong 271018, China Animal Husbandry Development and Promotion Center of Mengyin County, Linyi, Shandong 276200, China Animal Husbandry Development and Promotion Center of Mengyin County, Linyi, Shandong 276200, China Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Department of Animal Science, Shandong Agricultural University, Taian, Shandong 271018, China Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Department of Animal Science, Shandong Agricultural University, Taian, Shandong 271018, ChinaObjective Angora rabbits fed a low-protein diet exhibit decreased hair production performance. This study was set out to evaluate the effects of methionine on hair properties and nitrogen metabolism in Angora rabbits fed a low-protein diet and to investigate the gene expression related to hair follicle development to determine the possible molecular mechanism of methionine effects on hair follicle development. Methods An experiment was conducted to investigate the effects of DL-methionine addition on a low-protein diet on hair development in Angora rabbits. Angora rabbits were divided into 5 groups: fed a normal diet (control), fed a low-protein diet (LP), or fed an LP supplemented with 0.2%, 0.4%, or 0.6% DL-methionine (Met). Results The results showed that rabbits in the LP group had lower wool yield than the control rabbits, but the addition of 0.4% to 0.6% Met to LP attenuated these effects (p< 0.05). Dietary addition of 0.4% to 0.6% Met to LP increased the apparent nitrogen digestibility, nitrogen utilization rate, and feed efficiency (p<0.05). Feeding LP decreased the insulin-like growth factor 1 (IGF1), keratin-associated protein (KAP) 3.1, and KAP 6.1 mRNA levels compared with the control, but the addition of 0.4% Met in LP attenuated these effects (p<0.05). Relative to the LP or control group, dietary addition of 0.4% Met increased versican mRNA levels. Conclusion In conclusion, the addition of Met to LP could improves wool production performance and feed efficiency and reduce nitrogen emissions in Angora rabbits. Met can promote hair follicle development, which may be associated with IGF1, KAP, and the versican signaling.http://www.animbiosci.org/upload/pdf/ab-22-0286.pdfhair follicle growthlow protein dietmethioninenitrogen metabolism |
| spellingShingle | Man Zhao Tongtong Wang Bin Wang Chuanhua Liu Fuchang Li Lei Liu Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits Animal Bioscience hair follicle growth low protein diet methionine nitrogen metabolism |
| title | Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits |
| title_full | Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits |
| title_fullStr | Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits |
| title_full_unstemmed | Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits |
| title_short | Dietary methionine supplementation to a low-protein diet improved hair follicle development of Angora rabbits |
| title_sort | dietary methionine supplementation to a low protein diet improved hair follicle development of angora rabbits |
| topic | hair follicle growth low protein diet methionine nitrogen metabolism |
| url | http://www.animbiosci.org/upload/pdf/ab-22-0286.pdf |
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