Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin
Abstract Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-11-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.5136 |
| Summary: | Abstract Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose, started within two days of phenytoin. The too‐early dose intensification may have produced lamotrigine‐induced blood dyscrasia. |
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| ISSN: | 2050-0904 |