Synthesis of (2S,4S)-N-tert-butoxycarbonyl-4-fluoroproline
In order to overcome the difficulty to separate and purify the intermediate, solve the problem of quaternary ammonium salt removal,the synthesis of (2S,4S)-N-tert-butoxycarbonyl-4-fluoroproline which is a key intermediate of polypeptides and peptidomimetic drug is studied. The target compound is syn...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Hebei University of Science and Technology
2018-04-01
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| Series: | Journal of Hebei University of Science and Technology |
| Subjects: | |
| Online Access: | http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201802009&flag=1&journal_ |