Automated prediction of site and sequence of protein modification with ATRP initiators.
One of the most straightforward and commonly used chemical modifications of proteins is to react surface amino groups (lysine residues) with activated esters. This chemistry has been used to generate protein-polymer conjugates, many of which are now approved therapeutics. Similar conjugates have als...
Main Authors: | Arth Patel, Paige N Smith, Alan J Russell, Sheiliza Carmali |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0274606 |
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