Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review
Cutaneous mucormycosis typically occurs as a primary infection following traumatic inoculation or as a secondary disseminated disease in immunocompromised patients with hematologic malignancy or organ transplantation. We describe an unusual case of a poorly controlled type 1 diabetic patient present...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250921002250 |
| _version_ | 1819102040620531712 |
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| author | Samuel Phen Mir Ali Emily Hoff Kruti J. Yagnik James B. Cutrell John Waters Dominick Cavuoti Kehinde Odedosu |
| author_facet | Samuel Phen Mir Ali Emily Hoff Kruti J. Yagnik James B. Cutrell John Waters Dominick Cavuoti Kehinde Odedosu |
| author_sort | Samuel Phen |
| collection | DOAJ |
| description | Cutaneous mucormycosis typically occurs as a primary infection following traumatic inoculation or as a secondary disseminated disease in immunocompromised patients with hematologic malignancy or organ transplantation. We describe an unusual case of a poorly controlled type 1 diabetic patient presenting with wet gangrene of the hand due to angioinvasive dissemination from a primary pulmonary infection, with additional suspected foci of cardiac and central nervous system involvement. Despite combined medical and surgical treatment, the patient ultimately died due to complications of her infection. This case and the associated literature review of secondary cutaneous mucormycosis highlight that invasive fungal infections can present peripherally, and identifying the primary source is important in order to promptly pursue aggressive combined medical and surgical treatment for this highly fatal disease. |
| first_indexed | 2024-12-22T01:28:15Z |
| format | Article |
| id | doaj.art-a17ff5e039e048fa90a576dbbdf2b184 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-22T01:28:15Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-a17ff5e039e048fa90a576dbbdf2b1842022-12-21T18:43:33ZengElsevierIDCases2214-25092021-01-0126e01269Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature reviewSamuel Phen0Mir Ali1Emily Hoff2Kruti J. Yagnik3James B. Cutrell4John Waters5Dominick Cavuoti6Kehinde Odedosu7Parkland Health and Hospital Systems, Dallas, TX, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Division of Thoracic Surgery, Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Division of Thoracic Surgery, Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USAParkland Health and Hospital Systems, Dallas, TX, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA; Correspondence to: University of Texas Southwestern Medical Center, Parkland Health and Hospital Systems, 5323 Harry Hines Boulevard, Dallas, Texas 75390-8811, USA.Cutaneous mucormycosis typically occurs as a primary infection following traumatic inoculation or as a secondary disseminated disease in immunocompromised patients with hematologic malignancy or organ transplantation. We describe an unusual case of a poorly controlled type 1 diabetic patient presenting with wet gangrene of the hand due to angioinvasive dissemination from a primary pulmonary infection, with additional suspected foci of cardiac and central nervous system involvement. Despite combined medical and surgical treatment, the patient ultimately died due to complications of her infection. This case and the associated literature review of secondary cutaneous mucormycosis highlight that invasive fungal infections can present peripherally, and identifying the primary source is important in order to promptly pursue aggressive combined medical and surgical treatment for this highly fatal disease.http://www.sciencedirect.com/science/article/pii/S2214250921002250Disseminated mucormycosisCutaneous mucormycosisPulmonary mucormycosis |
| spellingShingle | Samuel Phen Mir Ali Emily Hoff Kruti J. Yagnik James B. Cutrell John Waters Dominick Cavuoti Kehinde Odedosu Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review IDCases Disseminated mucormycosis Cutaneous mucormycosis Pulmonary mucormycosis |
| title | Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review |
| title_full | Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review |
| title_fullStr | Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review |
| title_full_unstemmed | Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review |
| title_short | Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review |
| title_sort | left hand necrosis as the initial presentation of disseminated mucormycosis a case report and literature review |
| topic | Disseminated mucormycosis Cutaneous mucormycosis Pulmonary mucormycosis |
| url | http://www.sciencedirect.com/science/article/pii/S2214250921002250 |
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