The Epidemiology of Diabetic Kidney Disease

Globally, the incidence and prevalence of diabetes mellitus has risen dramatically, owing mainly to the increase in type 2 diabetes mellitus (T2DM). In 2021, 537 million people worldwide (11% of the global population) had diabetes, and this number is expected to increase to 783 million (12%) by 2045...

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Main Author: Ellen K. Hoogeveen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Kidney and Dialysis
Subjects:
Online Access:https://www.mdpi.com/2673-8236/2/3/38
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author Ellen K. Hoogeveen
author_facet Ellen K. Hoogeveen
author_sort Ellen K. Hoogeveen
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description Globally, the incidence and prevalence of diabetes mellitus has risen dramatically, owing mainly to the increase in type 2 diabetes mellitus (T2DM). In 2021, 537 million people worldwide (11% of the global population) had diabetes, and this number is expected to increase to 783 million (12%) by 2045. The growing burden of T2DM is secondary to the pandemic of obesity, which in turn has been attributed to increased intake of processed food, reduced physical activity, and increased sedentary behaviour. This so-called western lifestyle is related with the global increase in urbanization and technological development. One of the most frequent and severe long-term complications of diabetes is diabetic kidney disease (DKD), defined as chronic kidney disease in a person with diabetes. Approximately 20–50% of patients with T2DM will ultimately develop DKD. Worldwide, DKD is the leading cause of chronic kidney disease and end-stage kidney disease, accounting for 50% of cases. In addition, DKD results in high cardiovascular morbidity and mortality, and decreases patients’ health-related quality of life. In this review we provide an update of the diagnosis, epidemiology, and causes of DKD.
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spelling doaj.art-a18318cafbaf498e83e9f19747f92ebf2023-11-24T08:55:00ZengMDPI AGKidney and Dialysis2673-82362022-08-012343344210.3390/kidneydial2030038The Epidemiology of Diabetic Kidney DiseaseEllen K. Hoogeveen0Department of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsGlobally, the incidence and prevalence of diabetes mellitus has risen dramatically, owing mainly to the increase in type 2 diabetes mellitus (T2DM). In 2021, 537 million people worldwide (11% of the global population) had diabetes, and this number is expected to increase to 783 million (12%) by 2045. The growing burden of T2DM is secondary to the pandemic of obesity, which in turn has been attributed to increased intake of processed food, reduced physical activity, and increased sedentary behaviour. This so-called western lifestyle is related with the global increase in urbanization and technological development. One of the most frequent and severe long-term complications of diabetes is diabetic kidney disease (DKD), defined as chronic kidney disease in a person with diabetes. Approximately 20–50% of patients with T2DM will ultimately develop DKD. Worldwide, DKD is the leading cause of chronic kidney disease and end-stage kidney disease, accounting for 50% of cases. In addition, DKD results in high cardiovascular morbidity and mortality, and decreases patients’ health-related quality of life. In this review we provide an update of the diagnosis, epidemiology, and causes of DKD.https://www.mdpi.com/2673-8236/2/3/38chronic kidney diseasediabetes mellitusepidemiologyend-stage kidney disease
spellingShingle Ellen K. Hoogeveen
The Epidemiology of Diabetic Kidney Disease
Kidney and Dialysis
chronic kidney disease
diabetes mellitus
epidemiology
end-stage kidney disease
title The Epidemiology of Diabetic Kidney Disease
title_full The Epidemiology of Diabetic Kidney Disease
title_fullStr The Epidemiology of Diabetic Kidney Disease
title_full_unstemmed The Epidemiology of Diabetic Kidney Disease
title_short The Epidemiology of Diabetic Kidney Disease
title_sort epidemiology of diabetic kidney disease
topic chronic kidney disease
diabetes mellitus
epidemiology
end-stage kidney disease
url https://www.mdpi.com/2673-8236/2/3/38
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