Integrative genomic, proteomic and phenotypic studies of Leishmania donovani strains revealed genetic features associated with virulence and antimony-resistance

Integrative genomic, proteomic and phenotypic studies of Leishmania donovani strains revealed genetic features associated with virulence and antimony-resistance

Abstract Background Leishmaniasis is a neglected tropical disease affecting millions of people worldwide. Emerging drug resistance of Leishmania species poses threaten to the effective control and elimination programme of this neglected tropical disease. Methods In this work, we conducted drug-resis...

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Bibliographic Details
Main Authors: Zhiwan Zheng, Jianping Chen, Guangxu Ma, Abhay R. Satoskar, Jiao Li
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Parasites & Vectors
Subjects:
Leishmania donovani
Antimony resistance
Whole genome resequencing
Proteome profiling
Genetic variations
Online Access:http://link.springer.com/article/10.1186/s13071-020-04397-4

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