The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD

The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD

BackgroundAlthough studies suggest a deficiency in stem cell numbers in chronic airway diseases such as chronic obstructive pulmonary disease (COPD), the role of bronchial epithelial progenitor/stem (P/S) cells is not clear. The objectives of this study were to investigate expression of progenitor/s...

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Bibliographic Details
Main Authors: Nuray Bostancieri, Kemal Bakir, Seval Kul, Ayhan Eralp, Ozgecan Kayalar, Nur Konyalilar, Hadi Rajabi, Mehmet Yuncu, Ali Önder Yildirim, Hasan Bayram
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Medicine
Subjects:
COPD
smoker
progenitor/stem cell
primary bronchial epithelial cell culture
cytokeratin 5
cytokeratin 14
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1118715/full

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