Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients
BackgroundThis study determined the dose of remifentanil to use during insertion of a Classic™ laryngeal mask airway (LMA, The Laryngeal Mask Co., Nicosia, Cyprus) in elderly patients during emergency airway management when combined with a single dose of propofol.MethodsPatients aged 65-80 years wer...
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| Format: | Article |
| Language: | English |
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Korean Society of Anesthesiologists
2014-04-01
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| Series: | Korean Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://ekja.org/upload/pdf/kjae-66-278.pdf |
| _version_ | 1818081170548588544 |
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| author | Junghee Ryu Ah Young Oh Ji-Seok Baek Jin-Hee Kim Sang-Heon Park Jae-Mun Noh |
| author_facet | Junghee Ryu Ah Young Oh Ji-Seok Baek Jin-Hee Kim Sang-Heon Park Jae-Mun Noh |
| author_sort | Junghee Ryu |
| collection | DOAJ |
| description | BackgroundThis study determined the dose of remifentanil to use during insertion of a Classic™ laryngeal mask airway (LMA, The Laryngeal Mask Co., Nicosia, Cyprus) in elderly patients during emergency airway management when combined with a single dose of propofol.MethodsPatients aged 65-80 years were enrolled. Anesthesia was induced with propofol 1 mg/kg, and then a blinded dose of remifentanil was infused over 30 s after confirming the patient's loss of consciousness. The dose of remifentanil was determined using Dixon's up-and-down method, starting at 0.5 µg/kg (a step size of 0.1 µg/kg). Insertion of the LMA was attempted 60 s after loss of consciousness.ResultsIn total, 23 patients were recruited and the mean age ± standard deviation was 72 ± 3 years. The effective dose for successful LMA insertion in 50% of the patients (ED50) was 0.20 ± 0.05 µg/kg. No patient needed more than 0.3 µg/kg.ConclusionsRemifentanil 0.20 ± 0.05 µg/kg with propofol 1 mg/kg resulted in excellent LMA insertion in 50% of elderly patients without significant hemodynamic changes during emergency airway management. |
| first_indexed | 2024-12-10T19:01:57Z |
| format | Article |
| id | doaj.art-a185da2eca0f452b9358c79170a4d4a7 |
| institution | Directory Open Access Journal |
| issn | 2005-6419 2005-7563 |
| language | English |
| last_indexed | 2024-12-10T19:01:57Z |
| publishDate | 2014-04-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Korean Journal of Anesthesiology |
| spelling | doaj.art-a185da2eca0f452b9358c79170a4d4a72022-12-22T01:36:59ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632014-04-0166427828210.4097/kjae.2014.66.4.2787845Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patientsJunghee Ryu0Ah Young Oh1Ji-Seok Baek2Jin-Hee Kim3Sang-Heon Park4Jae-Mun Noh5Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hosptial, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hosptial, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hosptial, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hosptial, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hosptial, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hosptial, Seoul, Korea.BackgroundThis study determined the dose of remifentanil to use during insertion of a Classic™ laryngeal mask airway (LMA, The Laryngeal Mask Co., Nicosia, Cyprus) in elderly patients during emergency airway management when combined with a single dose of propofol.MethodsPatients aged 65-80 years were enrolled. Anesthesia was induced with propofol 1 mg/kg, and then a blinded dose of remifentanil was infused over 30 s after confirming the patient's loss of consciousness. The dose of remifentanil was determined using Dixon's up-and-down method, starting at 0.5 µg/kg (a step size of 0.1 µg/kg). Insertion of the LMA was attempted 60 s after loss of consciousness.ResultsIn total, 23 patients were recruited and the mean age ± standard deviation was 72 ± 3 years. The effective dose for successful LMA insertion in 50% of the patients (ED50) was 0.20 ± 0.05 µg/kg. No patient needed more than 0.3 µg/kg.ConclusionsRemifentanil 0.20 ± 0.05 µg/kg with propofol 1 mg/kg resulted in excellent LMA insertion in 50% of elderly patients without significant hemodynamic changes during emergency airway management.http://ekja.org/upload/pdf/kjae-66-278.pdfagedlaryngeal mask airwayremifentanil |
| spellingShingle | Junghee Ryu Ah Young Oh Ji-Seok Baek Jin-Hee Kim Sang-Heon Park Jae-Mun Noh Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients Korean Journal of Anesthesiology aged laryngeal mask airway remifentanil |
| title | Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| title_full | Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| title_fullStr | Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| title_full_unstemmed | Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| title_short | Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| title_sort | remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients |
| topic | aged laryngeal mask airway remifentanil |
| url | http://ekja.org/upload/pdf/kjae-66-278.pdf |
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