Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering

Exudates are the primary sign of Diabetic Retinopathy. Early detection can potentially reduce the risk of blindness. An automatic method to detect exudates from low-contrast digital images of retinopathy patients with non-dilated pupils using a Fuzzy C-Means (FCM) clustering is proposed. Contrast en...

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Main Authors: Akara Sopharak, Sarah Barman, Bunyarit Uyyanonvara
Format: Article
Language:English
Published: MDPI AG 2009-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/3/2148/
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author Akara Sopharak
Sarah Barman
Bunyarit Uyyanonvara
author_facet Akara Sopharak
Sarah Barman
Bunyarit Uyyanonvara
author_sort Akara Sopharak
collection DOAJ
description Exudates are the primary sign of Diabetic Retinopathy. Early detection can potentially reduce the risk of blindness. An automatic method to detect exudates from low-contrast digital images of retinopathy patients with non-dilated pupils using a Fuzzy C-Means (FCM) clustering is proposed. Contrast enhancement preprocessing is applied before four features, namely intensity, standard deviation on intensity, hue and a number of edge pixels, are extracted to supply as input parameters to coarse segmentation using FCM clustering method. The first result is then fine-tuned with morphological techniques. The detection results are validated by comparing with expert ophthalmologists’ hand-drawn ground-truths. Sensitivity, specificity, positive predictive value (PPV), positive likelihood ratio (PLR) and accuracy are used to evaluate overall performance. It is found that the proposed method detects exudates successfully with sensitivity, specificity, PPV, PLR and accuracy of 87.28%, 99.24%, 42.77%, 224.26 and 99.11%, respectively.
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spelling doaj.art-a1872117b32244eebb5db90222e645f52022-12-22T04:22:28ZengMDPI AGSensors1424-82202009-03-01932148216110.3390/s90302148Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means ClusteringAkara SopharakSarah BarmanBunyarit UyyanonvaraExudates are the primary sign of Diabetic Retinopathy. Early detection can potentially reduce the risk of blindness. An automatic method to detect exudates from low-contrast digital images of retinopathy patients with non-dilated pupils using a Fuzzy C-Means (FCM) clustering is proposed. Contrast enhancement preprocessing is applied before four features, namely intensity, standard deviation on intensity, hue and a number of edge pixels, are extracted to supply as input parameters to coarse segmentation using FCM clustering method. The first result is then fine-tuned with morphological techniques. The detection results are validated by comparing with expert ophthalmologists’ hand-drawn ground-truths. Sensitivity, specificity, positive predictive value (PPV), positive likelihood ratio (PLR) and accuracy are used to evaluate overall performance. It is found that the proposed method detects exudates successfully with sensitivity, specificity, PPV, PLR and accuracy of 87.28%, 99.24%, 42.77%, 224.26 and 99.11%, respectively.http://www.mdpi.com/1424-8220/9/3/2148/exudatesdiabetic retinopathynon-dilated retinal imagesFuzzy C-Means clustering
spellingShingle Akara Sopharak
Sarah Barman
Bunyarit Uyyanonvara
Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
Sensors
exudates
diabetic retinopathy
non-dilated retinal images
Fuzzy C-Means clustering
title Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
title_full Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
title_fullStr Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
title_full_unstemmed Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
title_short Automatic Exudate Detection from Non-dilated Diabetic Retinopathy Retinal Images Using Fuzzy C-means Clustering
title_sort automatic exudate detection from non dilated diabetic retinopathy retinal images using fuzzy c means clustering
topic exudates
diabetic retinopathy
non-dilated retinal images
Fuzzy C-Means clustering
url http://www.mdpi.com/1424-8220/9/3/2148/
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