Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products
Formaldehyde-free hair-straightening products are hair-smoothening solutions widely used by professional beauty salons. Formaldehyde-free hair straighteners do not technically contain formaldehyde; however, they contain other chemicals such as glyoxyloyl carbocysteine which releases formaldehyde upo...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2022-07-01
|
| Series: | Case Reports in Nephrology and Dialysis |
| Subjects: | |
| Online Access: | https://beta.karger.com/Article/FullText/525567 |
| _version_ | 1811221421748125696 |
|---|---|
| author | Nabil Abu-Amer Natalie Silberstein Margarita Kunin Sharon Mini Pazit Beckerman |
| author_facet | Nabil Abu-Amer Natalie Silberstein Margarita Kunin Sharon Mini Pazit Beckerman |
| author_sort | Nabil Abu-Amer |
| collection | DOAJ |
| description | Formaldehyde-free hair-straightening products are hair-smoothening solutions widely used by professional beauty salons. Formaldehyde-free hair straighteners do not technically contain formaldehyde; however, they contain other chemicals such as glyoxyloyl carbocysteine which releases formaldehyde upon contact with heat. Moreover, its by-product glyoxylate may convert to oxalate; both compounds have potential nephrotoxic effect. Here, we report a case of a 41-year-old woman who presented to the emergency room with weakness, nausea, vomiting, and stage 3 acute kidney injury (AKI) according to Kidney Disease: Improving Global Outcomes (KDIGO) acute kidney injury staging shortly after exposure to formaldehyde-free hair-straightening product; other causes of AKI were excluded such as preceding acute illness, drug history, or other nephrotoxic agent exposure. On physical examination, the patient was pale, and her vital signs were normal. The urine microscopy and serologic workup were not indicative. Kidney core biopsy revealed interstitial edema, acute interstitial nephritis, and oxalate crystal nephropathy. Kidney function completely recovered after a short course of steroid therapy. In this case, AKI was a complication caused by exposure to hair-straightening products branded as formaldehyde free but actually containing other chemical products which release formaldehyde and other toxic chemicals when heated during the straightening procedure and may cause systemic toxicity, particularly kidney injury. Different cosmetic products are widely in use, but not all are under tight regulation, and therefore, it is important to raise the awareness among both medical teams and consumers of possible adverse health effects of different cosmetic products. |
| first_indexed | 2024-04-12T07:59:02Z |
| format | Article |
| id | doaj.art-a18772dc78264c02bfc2d8fea25798b8 |
| institution | Directory Open Access Journal |
| issn | 2296-9705 |
| language | English |
| last_indexed | 2024-04-12T07:59:02Z |
| publishDate | 2022-07-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Nephrology and Dialysis |
| spelling | doaj.art-a18772dc78264c02bfc2d8fea25798b82022-12-22T03:41:23ZengKarger PublishersCase Reports in Nephrology and Dialysis2296-97052022-07-0112211211610.1159/000525567525567Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening ProductsNabil Abu-Amer0Natalie Silberstein1Margarita Kunin2Sharon Mini3Pazit Beckerman4Institute of Nephrology and Hypertension, Sheba Medical Center, Ramat Gan, IsraelInstitute of Nephrology and Hypertension, Sheba Medical Center, Ramat Gan, IsraelInstitute of Nephrology and Hypertension, Sheba Medical Center, Ramat Gan, IsraelInstitute of Nephrology and Hypertension, Sheba Medical Center, Ramat Gan, IsraelInstitute of Nephrology and Hypertension, Sheba Medical Center, Ramat Gan, IsraelFormaldehyde-free hair-straightening products are hair-smoothening solutions widely used by professional beauty salons. Formaldehyde-free hair straighteners do not technically contain formaldehyde; however, they contain other chemicals such as glyoxyloyl carbocysteine which releases formaldehyde upon contact with heat. Moreover, its by-product glyoxylate may convert to oxalate; both compounds have potential nephrotoxic effect. Here, we report a case of a 41-year-old woman who presented to the emergency room with weakness, nausea, vomiting, and stage 3 acute kidney injury (AKI) according to Kidney Disease: Improving Global Outcomes (KDIGO) acute kidney injury staging shortly after exposure to formaldehyde-free hair-straightening product; other causes of AKI were excluded such as preceding acute illness, drug history, or other nephrotoxic agent exposure. On physical examination, the patient was pale, and her vital signs were normal. The urine microscopy and serologic workup were not indicative. Kidney core biopsy revealed interstitial edema, acute interstitial nephritis, and oxalate crystal nephropathy. Kidney function completely recovered after a short course of steroid therapy. In this case, AKI was a complication caused by exposure to hair-straightening products branded as formaldehyde free but actually containing other chemical products which release formaldehyde and other toxic chemicals when heated during the straightening procedure and may cause systemic toxicity, particularly kidney injury. Different cosmetic products are widely in use, but not all are under tight regulation, and therefore, it is important to raise the awareness among both medical teams and consumers of possible adverse health effects of different cosmetic products.https://beta.karger.com/Article/FullText/525567acute interstitial nephritisacute kidney injurycosmetic productscrystal nephropathy |
| spellingShingle | Nabil Abu-Amer Natalie Silberstein Margarita Kunin Sharon Mini Pazit Beckerman Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products Case Reports in Nephrology and Dialysis acute interstitial nephritis acute kidney injury cosmetic products crystal nephropathy |
| title | Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products |
| title_full | Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products |
| title_fullStr | Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products |
| title_full_unstemmed | Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products |
| title_short | Acute Kidney Injury following Exposure to Formaldehyde-Free Hair-Straightening Products |
| title_sort | acute kidney injury following exposure to formaldehyde free hair straightening products |
| topic | acute interstitial nephritis acute kidney injury cosmetic products crystal nephropathy |
| url | https://beta.karger.com/Article/FullText/525567 |
| work_keys_str_mv | AT nabilabuamer acutekidneyinjuryfollowingexposuretoformaldehydefreehairstraighteningproducts AT nataliesilberstein acutekidneyinjuryfollowingexposuretoformaldehydefreehairstraighteningproducts AT margaritakunin acutekidneyinjuryfollowingexposuretoformaldehydefreehairstraighteningproducts AT sharonmini acutekidneyinjuryfollowingexposuretoformaldehydefreehairstraighteningproducts AT pazitbeckerman acutekidneyinjuryfollowingexposuretoformaldehydefreehairstraighteningproducts |