IL-17 Aggravates Pseudomonas aeruginosa Airway Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

IL-17 Aggravates Pseudomonas aeruginosa Airway Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pseudomonas aeruginosa airway infection increases risks of exacerbations and mortality in chronic obstructive pulmonary disease (COPD). We aimed to elucidate the role of IL-17 in the pathogenesis. We examined the expression and influences of IL-23/IL-17A in patients with stable COPD (n = 33) or acut...

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Bibliographic Details
Main Authors: Fengming Ding, Lei Han, Qiang Fu, Xinxin Fan, Rong Tang, Chengjian Lv, Yishu Xue, Xue Tian, Min Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
COPD
IL-17
Pseudomonas aeruginosa
cytokine profile
lung function
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.811803/full

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