A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses
Abstract Salicylic acid (SA) plays a crucial regulatory role in plant immunity. NPR1 (non-expressor of pathogenesis related-1) is a SA receptor and plays a pivotal role in SA signaling. However, pathogen effectors which target NPR1 to promote infection have rarely been reported. Here, we identified...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-02-01
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| Series: | Phytopathology Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s42483-019-0013-y |
| _version_ | 1818148333413203968 |
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| author | Qi Li Yanyu Chen Ji Wang Fen Zou Yuling Jia Danyu Shen Qimeng Zhang Maofeng Jing Daolong Dou Meixiang Zhang |
| author_facet | Qi Li Yanyu Chen Ji Wang Fen Zou Yuling Jia Danyu Shen Qimeng Zhang Maofeng Jing Daolong Dou Meixiang Zhang |
| author_sort | Qi Li |
| collection | DOAJ |
| description | Abstract Salicylic acid (SA) plays a crucial regulatory role in plant immunity. NPR1 (non-expressor of pathogenesis related-1) is a SA receptor and plays a pivotal role in SA signaling. However, pathogen effectors which target NPR1 to promote infection have rarely been reported. Here, we identified a Phytophthora capsici effector RxLR48 that associates with NPR1, facilitates P. capsici infection and is required for pathogen virulence. Furthermore, we demonstrated that RxLR48 promotes NPR1’s nuclear localization and inhibits its proteasome-mediated degradation, suggesting that RxLR48 suppresses SA signaling by targeting the central regulator NPR1. In addition, we showed that RxLR48 also suppresses pattern-triggered immunity (PTI). Together, our research indicates that P. capsici suppresses plant immunity by targeting SA and PTI pathways. |
| first_indexed | 2024-12-11T12:49:28Z |
| format | Article |
| id | doaj.art-a18a7ae2a06944b6906213d6e13b48bf |
| institution | Directory Open Access Journal |
| issn | 2524-4167 |
| language | English |
| last_indexed | 2024-12-11T12:49:28Z |
| publishDate | 2019-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Phytopathology Research |
| spelling | doaj.art-a18a7ae2a06944b6906213d6e13b48bf2022-12-22T01:06:45ZengBMCPhytopathology Research2524-41672019-02-011111110.1186/s42483-019-0013-yA Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responsesQi Li0Yanyu Chen1Ji Wang2Fen Zou3Yuling Jia4Danyu Shen5Qimeng Zhang6Maofeng Jing7Daolong Dou8Meixiang Zhang9Department of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityDepartment of Plant Pathology, Nanjing Agricultural UniversityAbstract Salicylic acid (SA) plays a crucial regulatory role in plant immunity. NPR1 (non-expressor of pathogenesis related-1) is a SA receptor and plays a pivotal role in SA signaling. However, pathogen effectors which target NPR1 to promote infection have rarely been reported. Here, we identified a Phytophthora capsici effector RxLR48 that associates with NPR1, facilitates P. capsici infection and is required for pathogen virulence. Furthermore, we demonstrated that RxLR48 promotes NPR1’s nuclear localization and inhibits its proteasome-mediated degradation, suggesting that RxLR48 suppresses SA signaling by targeting the central regulator NPR1. In addition, we showed that RxLR48 also suppresses pattern-triggered immunity (PTI). Together, our research indicates that P. capsici suppresses plant immunity by targeting SA and PTI pathways.http://link.springer.com/article/10.1186/s42483-019-0013-yPhytophthoraArabidopsis thalianaNPR1EffectorVirulencePTI |
| spellingShingle | Qi Li Yanyu Chen Ji Wang Fen Zou Yuling Jia Danyu Shen Qimeng Zhang Maofeng Jing Daolong Dou Meixiang Zhang A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses Phytopathology Research Phytophthora Arabidopsis thaliana NPR1 Effector Virulence PTI |
| title | A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses |
| title_full | A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses |
| title_fullStr | A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses |
| title_full_unstemmed | A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses |
| title_short | A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses |
| title_sort | phytophthora capsici virulence effector associates with npr1 and suppresses plant immune responses |
| topic | Phytophthora Arabidopsis thaliana NPR1 Effector Virulence PTI |
| url | http://link.springer.com/article/10.1186/s42483-019-0013-y |
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